ArticleJournal of the International AIDS Society2020
Directed and target focused multi-sectoral adolescent HIV prevention: Insights from implementation of the 'DREAMS Partnership' in rural South Africa.
Article in Journal of the International AIDS Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed, 70 citations in OpenAlex.
- Trial
- Trial
- The impact of financial incentives on HIV incidence among adolescent girls and young women in Eswatini: Sitakhela Likusasa, a cluster randomised trial.BMJ global health · 2022Trial
- Thetha Nami: participatory development of a peer-navigator intervention to deliver biosocial HIV prevention for adolescents and youth in rural South Africa.BMC public health · 2021Trial
- Effect of peer-distributed HIV self-test kits on demand for biomedical HIV prevention in rural KwaZulu-Natal, South Africa: a three-armed cluster-randomised trial comparing social networks versus direct delivery.BMJ global health · 2021Trial
- Article
- Integrating PrEP and Sexual Reproductive Health Services for Adolescent Girls and Young Women in South Africa: A Scoping Review.AIDS and behavior · 2026Review
- Article
- How can complex interventions be adapted to context? A qualitative analysis of the implementation of DREAMS in three Kenyan settings.PLOS global public health · 2026Article
- Challenges and opportunities in achieving sustainable development goal 3 in KwaZulu-Natal: reflections from a research institute, South Africa.BMC public health · 2025Review
- Experiences of adolescent girls and young women of oral PrEP uptake in rural KwaZulu-Natal.African journal of primary health care & family medicine · 2025Article
- Masibambane (Let Us Work Together), Ladies Chat: Pilot Evaluation of an Online, Gender-Enhanced, Group-Interactive Workshop to Promote Oral PrEP to Young South African Women.AIDS and behavior · 2025Article
- Differences in HIV risk factors between South African adolescents and adult women and their association with sexually transmitted infections.Sexually transmitted infections · 2025Observational
- Navigating socio-ecological and institutional barriers to antiretroviral therapy adherence: qualitative insights among young men and women from Nairobi's informal settlements.Frontiers in public health · 2025Article
- Barriers and facilitators to oral pre-exposure prophylaxis uptake among adolescents girls and young women at elevated risk of HIV acquisition in Lilongwe, Malawi: A qualitative study.PLOS global public health · 2025Article
- Understanding the mental health of adolescents and young adults in rural South Africa through participatory research.PLOS global public health · 2025Article
- The effect of multi-level HIV prevention interventions on common mental disorders among adolescents and young adults in rural South Africa.PLOS global public health · 2025Article
- Gender-transformative HIV and SRHR programme approaches for adolescents and young people: a realist review to inform policy and programmes.BMJ global health · 2024Review
- Uptake of multi-level HIV interventions and HIV-related behaviours among young people in rural South Africa.PLOS global public health · 2024Article
- Evidence of HIV incidence reduction in young women, but not in adolescent girls, in KwaZulu-Natal, South Africa.IJID regions · 2023Article
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Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
Abstract
introductionThe "DREAMS Partnership" promotes a multi-sectoral approach to reduce adolescent girls and young women's (AGYW) vulnerability to HIV in sub-Saharan Africa. Despite widespread calls to combine structural, behavioural and biomedical HIV prevention interventions, this has not been delivered at scale. In this commentary, we reflect on the two-year rollout of DREAMS in a high HIV incidence, rural and poor community in northern KwaZulu-Natal, South Africa to critically appraise the capacity for a centrally co-ordinated and AGYW-focused approach to combination HIV prevention to support sustainable development for adolescents. DISCUSSION: DREAMS employed a directed target-focused approach in which local implementing partners were resourced to deliver defined packages to AGYW in selected geographical areas over two years. We argue that this approach, with high-level oversight by government and funders, enabled the rapid roll-out of ambitious multi-sectoral HIV prevention for AGYW. It was most successful at delivering multiple interventions for AGYW when it built on existing infrastructure and competencies, and/or allocated resources to address existing youth development concerns of the community. The approach would have been strengthened if it had included a mechanism to solicit and then respond to the concerns of young women, for example gender-related norms and how young women experience their sexuality, and if this listening was supported by versatility to adapt to the social context. In a context of high HIV vulnerability across all adolescents and youth, an over-emphasis on targeting specific groups, whether geographically or by risk profile, may have hampered acceptability and reach of the intervention. Absence of meaningful engagement of AGYW in the development, delivery and leadership of the intervention was a lost opportunity to achieve sustainable development goals among young people and shift gender-norms.
conclusionsCentrally directed and target-focused scale-up of defined packages of HIV prevention across sectors was largely successful in reaching AGYW in this rural South African setting rapidly. However, to achieve sustainable and successful long-term youth development and transformation of gender-norms there is a need for greater adaptability, economic empowerment and meaningful engagement of AGYW in the development and delivery of interventions. Achieving this will require sustained commitment from government and funders.
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