Evidence map›Paper›PMID 32869144›Full record

ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2021

Revisiting the Value of Drains After Low Anterior Resection for Rectal Cancer: a Multi-institutional Analysis of 996 Patients.

Rachel M Lee, Adriana C Gamboa, Michael K Turgeon, Sanjana Prasad, Gifty Kwakye, Maryam Mohammed, Jennifer Holder-Murray, Sherif Abdel-Misih, Charles Kimbrough, Mosope Soda and 5 more

Open access · greenAbstract read
In one paragraph

Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 1 country.

Rachel M LeeDivision of Surgical Oncology, Department of Surgery, Winship Cancer Institute, Emory University, Atlanta, GA, USA.ORCID 0000-0003-2704-839X
Adriana C GamboaDivision of Surgical Oncology, Department of Surgery, Winship Cancer Institute, Emory University, Atlanta, GA, USA.
Michael K TurgeonDivision of Surgical Oncology, Department of Surgery, Winship Cancer Institute, Emory University, Atlanta, GA, USA.
Sanjana PrasadDivision of Colorectal Surgery, Department of Surgery, University of Michigan, Ann Arbor, MI, USA.
Gifty KwakyeDivision of Colorectal Surgery, Department of Surgery, University of Michigan, Ann Arbor, MI, USA.
Maryam MohammedDivision of Colon and Rectal Surgery, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Jennifer Holder-MurrayDivision of Colon and Rectal Surgery, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Sherif Abdel-MisihDivision of Surgical Oncology, Department of Surgery, The Ohio State University, Columbus, OH, USA.
Charles KimbroughDivision of Surgical Oncology, Department of Surgery, The Ohio State University, Columbus, OH, USA.
Mosope SodaSection of Colon & Rectal Surgery, Division of General Surgery, Vanderbilt University Medical Center, St. Louis, MO, USA.
Alexander T HawkinsSection of Colon & Rectal Surgery, Division of General Surgery, Vanderbilt University Medical Center, St. Louis, MO, USA.
William C ChapmanSection of Colon & Rectal Surgery, Department of Surgery, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.
Matthew SilvieraSection of Colon & Rectal Surgery, Department of Surgery, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.
Shishir K MaithelDivision of Surgical Oncology, Department of Surgery, Winship Cancer Institute, Emory University, Atlanta, GA, USA.
Glen BalchDivision of Colon & Rectal Surgery, Department of Surgery, Emory University, 1364 Clifton Road, Atlanta, GA, 30322, USA. glen.c.balch@emory.edu.
Emory University · USThe Ohio State University · USUniversity of Michigan · USUniversity of Pittsburgh Medical Center · USVanderbilt University Medical Center · USWashington University in St. Louis · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
J: NRSA Training CoreTL1TR002382 · NCATS · EMORY UNIVERSITY · PI HENRY M BLUMBERG, Vasiliki Michopoulos · 2017 to 2026
$8.5M
NCATS NIH HHS TL1 TR002382NCATS NIH HHS UL1 TR002378
6 · The paper itself

Abstract

backgroundIntraoperative pelvic drains are often placed during low anterior resection (LAR) to evacuate postoperative fluid collections and identify/control potential anastomotic leaks. Our aim was to assess the validity of this practice.

methodsPatients from the US Rectal Cancer Consortium (2007-2017) who underwent curative-intent LAR for a primary rectal cancer were included. Patients were categorized as receiving a closed suction drain intraoperatively or not. Primary outcomes were superficial surgical site infection (SSI), deep SSI, intraabdominal abscess, anastomotic leak, and need for secondary drain placement. Three subgroup analyses were conducted in patients who received neoadjuvant chemoradiation, had a diverting loop ileostomy (DLI), and had low anastomoses < 6 cm from the anal verge.

resultsOf 996 patients 67% (n = 551) received a drain. Drain patients were more likely to be male (64 vs 54%), have a smoking history (25 vs 19%), have received neoadjuvant chemoradiation (73 vs 61%), have low tumors (56 vs 36%), and have received a DLI (80 vs 71%) (all p < 0.05). Drains were associated with an increased anastomotic leak rate (14 vs 8%, p = 0.041), although there was no difference in the need for a secondary drainage procedure to control the leak (82 vs 88%, p = 0.924). These findings persisted in all subset analyses. Drains were not associated with increased superficial SSI, deep SSI, or intraabdominal abscess in the entire cohort or each subset analysis. Reoperation (12 vs 10%, p = 0.478) and readmission rates (28 vs 31%, p = 0.511) were similar.

conclusionsAlthough not associated with increased infectious complications, intraoperatively placed pelvic drains after low anterior resection for rectal cancer are associated with an increase in anastomotic leak rate and no reduction in the need for secondary drain placement or reoperation. Routine drainage appears to be unnecessary.

Indexed as

Rectal NeoplasmsAnastomosis, SurgicalAnastomotic LeakDrainageFemaleHumansIleostomyMaleRetrospective StudiesClosed suction drainLow anterior resectionRectal cancer

Identifiers

PMID32869144
PMCPMC7970451
OpenAlexW3081545912

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.