Evidence map›Paper›PMID 32869127›Full record

ArticleObesity surgery2020

Diabetes Remission and Relapse After Bariatric Surgery: a Nationwide Population-Based Study.

C Conte, M Lapeyre-Mestre, H Hanaire, P Ritz

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Article in Obesity surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  15. Managing obesity in people with type 2 diabetes.Clinical medicine (London, England) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

C ConteClinical Pharmacology Department, Toulouse University Hospital, Toulouse, France.
M Lapeyre-MestreClinical Pharmacology Department, Toulouse University Hospital, Toulouse, France.
H HanaireDiabetes Department, Toulouse CIO (Obesity Medicine Reference Center) and CHU (University Hospital), Toulouse, France.
P RitzInserm unit 1027, University of Toulouse 3, Toulouse, France. Patrick.ritz@wanadoo.fr.ORCID http://orcid.org/0000-0001-8105-4008

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe long-term impact of bariatric surgery on the remission of type 2 diabetes (T2DM) remains to be clarified through large nationally representative cohorts. The objectives were to determine the incidence of T2DM remission and relapse after bariatric surgery, to determine the factors associated with remission and to establish a profile for patients at risk for relapse. MATERIALS AND

methodsWe conducted a population-based cohort study using data from the French national health insurance database (Systeme national des données de santé [SNDS]). We had access to exhaustive regional data between 2013 and 2017 and to a national representative sample of the French population (EGB) from 2008 to 2018. Patients were included if they were adults and diabetics with incidental bariatric surgery.

resultsThis study shows that 50% of patients are in remission from diabetes after bariatric surgery within a median of 2 to 4 months. Diabetes relapse was observed in 13-20% within 10 years. The factors favouring remission already described were noted (non-insulin-dependent diabetes) and original factors were also identified, in particular the advantage of bypass surgery over sleeve gastrectomy, with more remissions and fewer relapses.

conclusionThis study highlights a 50% prevalence of remission and a low prevalence of relapse. There are non-modifiable risk factors for remission and relapse (characteristics of diabetes, age, lipid-lowering therapy) and modifiable factors (type of surgery). Identifying these factors is essential for optimal management of patients. Additional data are essential to confirm the results of our analysis of the factors associated with relapse.

Indexed as

Bariatric SurgeryDiabetes Mellitus, Type 2Obesity, MorbidAdultCohort StudiesGastrectomyHumansRecurrenceRemission InductionTreatment OutcomeBariatric surgeryDiabetesFrench national health insurance database (Systeme national des données de santé [SNDS])Obesity

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.