ArticleEuropean radiology experimental2020
Effect of CT imaging on the accuracy of the finite element modelling in bone.
Article in European radiology experimental, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Investigating the Influence of Limited CT Scan Coverage Using an Automated Workflow with Biofidelic Sideways Fall FE Models.Annals of biomedical engineering · 2026Article
- Bone Evaluation with Micro Finite Element Analysis in Animal Models.Tomography (Ann Arbor, Mich.) · 2025Review
- BoneDat, a database of standardized bone morphology for in silico analyses.Scientific data · 2025Article
- Impact of asymmetric L4-L5 facet joint degeneration on lumbar spine biomechanics using a finite element approach.Scientific reports · 2025Article
- Gender differences in L1 vertebral strength in adults 50+ using automated CT-based finite element analysis.Scientific reports · 2025Article
- Asynchronous calibration of a CT scanner for bone mineral density estimation: sources of error and correction.JBMR plus · 2024Article
- Opportunistic application of phantom-less calibration methods for fracture risk prediction using QCT/FEA.European radiology · 2021Article
- Finite Element Method for the Evaluation of the Human Spine: A Literature Overview.Journal of functional biomaterials · 2021Review
- Reduction Quality Determines Failure Behavior in Stable Intertrochanteric Fractures: A Mesh-Free Simulation Comparing DHS and TFNA.JB & JS open accessArticle
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Authors and funding
3 authors.
Funding
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Abstract
The finite element (FE) analysis is a highly promising tool to simulate the behaviour of bone. Skeletal FE models in clinical routine rely on the information about the geometry and bone mineral density distribution from quantitative computed tomography (CT) imaging systems. Several parameters in CT imaging have been reported to affect the accuracy of FE models. FE models of bone are exclusively developed in vitro under scanning conditions deviating from the clinical setting, resulting in variability of FE results (< 10%). Slice thickness and field of view had little effect on FE predicted bone behaviour (≤ 4%), while the reconstruction kernels showed to have a larger effect (≤ 20%). Due to large interscanner variations (≤ 20%), the translation from an experimental model into clinical reality is a critical step. Those variations are assumed to be mostly caused by different "black box" reconstruction kernels and the varying frequency of higher density voxels, representing cortical bone. Considering the low number of studies together with the significant effect of CT imaging on the finite element model outcome leading to high variability in the predicted behaviour, we propose further systematic research and validation studies, ideally preceding multicentre and longitudinal studies.
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