Evidence map›Paper›PMID 32868988›Full record

ArticleRespiratory medicine case reports2020

Alveolar proteinosis due to toxic inhalation at workplace.

Gabriela F Santos, João Portela, Despoina Argyropoulou, Rita Varudo, Inês Pimenta, Ana Oliveira, Sara Lança, Antero Fernandes

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory medicine case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. A Comprehensive Outlook on Pulmonary Alveolar Proteinosis-A Review.International journal of molecular sciences · 2024
    Review
  2. A comprehensive summary of disease variants implicated in metal allergy.Journal of toxicology and environmental health. Part B, Critical reviews · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gabriela F SantosPneumonology Department, Hospital Garcia de Orta, Av. Torrado da Silva, 2805-267, Almada, Portugal.
João PortelaPneumonology Department, Hospital Garcia de Orta, Av. Torrado da Silva, 2805-267, Almada, Portugal.
Despoina ArgyropoulouPathology Department, Hospital Garcia de Orta, Av. Torrado da Silva, 2805-267, Almada, Portugal.
Rita VarudoIntensive Care Department, Hospital Garcia de Orta, Av. Torrado da Silva, 2805-267, Almada, Portugal.
Inês PimentaIntensive Care Department, Hospital Garcia de Orta, Av. Torrado da Silva, 2805-267, Almada, Portugal.
Ana OliveiraPathology Department, Hospital Garcia de Orta, Av. Torrado da Silva, 2805-267, Almada, Portugal.
Sara LançaIntensive Care Department, Hospital Garcia de Orta, Av. Torrado da Silva, 2805-267, Almada, Portugal.
Antero FernandesIntensive Care Department, Hospital Garcia de Orta, Av. Torrado da Silva, 2805-267, Almada, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a clinical case of a 39-year old male, without any known previous medical condition but with occupational exposure to paints and dust cement, who presented an autoimmune pulmonary alveolar proteinosis (PAP) triggered by exposure to toxic inhalation at his workplace. PAP is a rare lung disease characterized by intra-alveolar abnormal accumulation of surfactant. The presence of a crazy-paving pattern in high-resolution computed tomography scan brings the suspicion of PAP although histopathology results of bronchoalveolar lavage are always required for its final diagnosis. The autoimmune form of PAP due to toxic inhalation, such as the one here described, is rare and it is usually difficult to establish a causal relationship.

Indexed as

Alveolar proteinosisAutoimmunityHypoxemiaRare lung diseaseToxic inhalation

Identifiers

PMID32868988
PMCPMC7449138

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.