SynthesisScientific reports2020
Meta-analysis of GWAS in canola blackleg (Leptosphaeria maculans) disease traits demonstrates increased power from imputed whole-genome sequence.
Synthesis in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Data Integration, Imputation, and Meta-analysis for Genome-Wide Association Studies.Methods in molecular biology (Clifton, N.J.) · 2022Pooled it
- Genome-wide modelling of plant transcription factor binding captures regulatory variants associated with phenotypic traits.Nature communications · 2026Article
- Establishing standards for genome wide association studies in eusocial insects through a case study in honey bees.Scientific reports · 2026Article
- Novel Molecular Markers and Immune-Related Candidate Genes for Blackleg Resistance in Rapeseed: A Genome-Wide Analysis.International journal of molecular sciences · 2026Article
- Discovery of the loci associated with the test weight and capsule seed weight variation in Sesame (Sesamum indicum L.).Plant molecular biology · 2026Article
- Stable pleotropic loci controlling the accumulation of multiple nutritional elements in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Article
- Using genotype imputation to integrate Canola populations for genome-wide association and genomic prediction of blackleg resistance.BMC genomics · 2025Article
- GWAS for identification of genomic regions and candidate genes in vegetable crops.Functional & integrative genomics · 2024Review
- DArTseq-Based, High-Throughput Identification of Novel Molecular Markers for the Detection of Blackleg (International journal of molecular sciences · 2024Article
- Identification of novel genes associated with herbicide tolerance in Lentil (Lens culinaris ssp. culinaris Medik.).Scientific reports · 2024Article
- Integration of genome-wide association studies, metabolomics, and transcriptomics reveals phenolic acid- and flavonoid-associated genes and their regulatory elements under drought stress in rapeseed flowers.Frontiers in plant science · 2023Article
- Identification of candidate genes forFrontiers in plant science · 2023Article
- Genome-wide association studies dissect the G × E interaction for agronomic traits in a worldwide collection of safflowers (Molecular breeding : new strategies in plant improvement · 2022Article
- Two decades of association mapping: Insights on disease resistance in major crops.Frontiers in plant science · 2022Review
- Genome-wide association study and transcriptome analysis dissect the genetic control of silique length in Brassica napus L.Biotechnology for biofuels · 2021Article
- QTL Mapping and GWAS Reveal the Genetic Mechanism Controlling Soluble Solids Content inFoods (Basel, Switzerland) · 2021Article
- Status and advances in mining for blackleg (Leptosphaeria maculans) quantitative resistance (QR) in oilseed rape (Brassica napus).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Review
- Meta-analysis of genome-wide association studies reveal common loci controlling agronomic and quality traits in a wide range of normal and heat stressed environments.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Genome-wide association study of multiple traits linked to heat tolerance in emmer-derived hexaploid wheat genotypes.Molecular breeding : new strategies in plant improvement · 2021Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Blackleg disease causes yield losses in canola (Brassica napus L.). To identify resistance genes and genomic regions, genome-wide association studies (GWAS) of 585 diverse winter and spring canola accessions were performed using imputed whole-genome sequence (WGS) and transcriptome genotype-by-sequencing (GBSt). Blackleg disease phenotypes were collected across three years in six trials. GWAS were performed in several ways and their respective power was judged by the number of significant single nucleotide polymorphisms (SNP), the false discovery rate (FDR), and the percentage of SNP that validated in additional field trials in two subsequent years. WGS GWAS with 1,234,708 million SNP detected a larger number of significant SNP, achieved a lower FDR and a higher validation rate than GBSt with 64,072 SNP. A meta-analysis combining survival and average internal infection resulted in lower FDR but also lower validation rates. The meta-analysis GWAS identified 79 genomic regions (674 SNP) conferring potential resistance to L. maculans. While several GWAS signals localised in regions of known Rlm genes, fifty-three new potential resistance regions were detected. Seventeen regions had underlying genes with putative functions related to disease defence or stress response in Arabidopsis thaliana. This study provides insight into the genetic architecture and potential molecular mechanisms underlying canola L. maculans resistance.
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