Evidence map›Paper›PMID 32868490›Full record

ArticleMolecules and cells2020

Evolutionary and Functional Analysis of Korean Native Pig Using Single Nucleotide Polymorphisms.

Jongin Lee, Nayoung Park, Daehwan Lee, Jaebum Kim

Open access · greenAbstract read
In one paragraph

Article in Molecules and cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. The Genetic Selection ofAnimals : an open access journal from MDPI · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jongin LeeDepartment of Biomedical Science and Engineering, Konkuk University, Seoul 05029, Korea.ORCID https://orcid.org/0000-0001-7870-1526
Nayoung ParkDepartment of Biomedical Science and Engineering, Konkuk University, Seoul 05029, Korea.ORCID https://orcid.org/0000-0003-2722-0639
Daehwan LeeDepartment of Biomedical Science and Engineering, Konkuk University, Seoul 05029, Korea.ORCID https://orcid.org/0000-0002-7210-0786
Jaebum KimDepartment of Biomedical Science and Engineering, Konkuk University, Seoul 05029, Korea.ORCID https://orcid.org/0000-0002-2287-9760
Konkuk University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Time and cost-effective production of next-generation sequencing data has enabled the performance of population-scale comparative and evolutionary studies for various species, which are essential for obtaining the comprehensive insight into molecular mechanisms underlying species- or breed-specific traits. In this study, the evolutionary and functional analysis of Korean native pig (KNP) was performed using single nucleotide polymorphism (SNP) data by comparative and population genomic approaches with six different mammalian species and five pig breeds. We examined the evolutionary history of KNP SNPs, and the specific genes of KNP based on the uniqueness of non-synonymous SNPs among the used species and pig breeds. We discovered the evolutionary trajectory of KNP SNPs within the used mammalian species as well as pig breeds. We also found olfaction-associated functions that have been characterized and diversified during evolution, and quantitative trait loci associated with the unique traits of KNP. Our study provides new insight into the evolution of KNP and serves as a good example for a better understanding of domestic animals in terms of evolution and domestication using the combined approaches of comparative and population genomics.

Indexed as

AnimalsEvolution, MolecularHigh-Throughput Nucleotide SequencingPolymorphism, Single NucleotideRepublic of KoreaSwinedomesticationevolutionKorean native pigsingle nucleotide polymorphism

Identifiers

PMID32868490
PMCPMC7468586
OpenAlexW3081542411

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.