Evidence map›Paper›PMID 32868471›Full record

ArticlePediatrics2020

Legal Performance-Enhancing Substances and Substance Use Problems Among Young Adults.

Kyle T Ganson, Deborah Mitchison, Stuart B Murray, Jason M Nagata

Open access · greenAbstract read
In one paragraph

Article in Pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Kyle T GansonFactor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Ontario, Canada.
Deborah MitchisonTranslational Health Research Institute, School of Medicine, Western Sydney University, Sydney, New South Wales, Australia.
Stuart B MurrayDepartment of Psychiatry and the Behavioral Sciences, University of Southern California, Los Angeles, California; and.
Jason M NagataDivision of Adolescent and Young Adult Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, California jasonmnagata@gmail.com.
University of California, San Francisco · USUniversity of Southern California · USUniversity of Toronto · CAWestern Sydney University · AU

Funding

Wave IV Data CollectionP01HD031921 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRIS, KATHLEEN MULLAN · 1994 to 2020
$86.1M
Fear Conditioning and Fear Extinction in Anorexia NervosaK23MH115184 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MURRAY, STUART B · 2017 to 2021
$990k
NICHD NIH HHS P01 HD031921NIMH NIH HHS K23 MH115184
6 · The paper itself

Abstract

backgroundLegal performance-enhancing substance(s) (PES) (eg, creatine) are widely used among adolescent boys and young men; however, little is known about their temporal associations with substance use behaviors.

methodsWe analyzed prospective cohort data from the National Longitudinal Study of Adolescent to Adult Health, Waves I to IV (1994-2008). Logistic regressions were used to first assess adolescent substance use (Wave I) and use of legal PES (Wave III) and second to assess use of legal PES (Wave III) and subsequent substance use-associated risk behaviors (Wave IV), adjusting for potential confounders.

resultsAmong the sample of 12 133 young adults aged 18 to 26 years, 16.1% of young men and 1.2% of young women reported using legal PES in the past year. Adolescent alcohol use was prospectively associated with legal PES use in young men (odds ratio 1.39; 95% confidence interval [CI] 1.13-1.70). Among young men, legal PES use was prospectively associated with higher odds of problematic alcohol use and drinking-related risk behaviors, including binge drinking (adjusted odds ratio [aOR] 1.35; 95% CI 1.07-1.71), injurious and risky behaviors (aOR 1.78; 95% CI 1.43-2.21), legal problems (aOR 1.52; 95% CI 1.08-2.13), cutting down on activities and socialization (aOR 1.91; 95% CI 1.36-2.78), and emotional or physical health problems (aOR 1.44; 95% CI 1.04-1.99). Among young women, legal PES use was prospectively associated with higher odds of emotional or physical health problems (aOR 3.00; 95% CI 1.20-7.44).

conclusionsUse of legal PES should be considered a gateway to future problematic alcohol use and drinking-related risk behaviors, particularly among young men.

Indexed as

AdolescentAdultAlcohol DrinkingAlcoholic IntoxicationAmino AcidsAthletesBody Mass IndexConfidence IntervalsCreatineDehydroepiandrosteroneFemaleHumansLogistic ModelsMaleMarijuana SmokingOdds RatioAmino AcidsCreatineDehydroepiandrosteronePerformance-Enhancing SubstancesSteroids

Identifiers

PMID32868471
PMCPMC7461208
OpenAlexW3082142004

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.