ArticleBMJ open2020
Predictors of postpartum glucose intolerance in women with gestational diabetes mellitus: a prospective cohort study in Ethiopia based on the updated diagnostic criteria.
Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Prediction Models for Maternal and Offspring Short- and Long-Term Outcomes Following Gestational Diabetes: A Systematic Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025Pooled it
- Models Predicting Postpartum Glucose Intolerance Among Women with a History of Gestational Diabetes Mellitus: a Systematic Review.Current diabetes reports · 2023Pooled it
- Development and validation of a risk prediction model for dysglycaemia at 6-12 weeks postpartum in Chinese women with gestational diabetes: a retrospective cohort study.Diabetology & metabolic syndrome · 2026Article
- Fasting glucose levels at diagnosis and delivery are associated with postpartum glucose abnormalities in GDM women.Archives of gynecology and obstetrics · 2025Article
- Prevalence of postpartum glucose intolerance and its association with physical activity levels among women with prior gestational diabetes mellitus attending public primary care clinics in Penang: A cross-sectional study.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2025Article
- Metabolic profiling identifies potential biomarkers associated with progression from gestational diabetes mellitus to prediabetes postpartum.Journal of biomedical research · 2024Article
- Risk prediction models for postpartum glucose intolerance in women with a history of gestational diabetes mellitus: a scoping review.Journal of diabetes and metabolic disorders · 2024Article
- Article
- Digital Health and Machine Learning Technologies for Blood Glucose Monitoring and Management of Gestational Diabetes.IEEE reviews in biomedical engineering · 2024Review
- Development and validation of a risk score to predict adverse birth outcomes using maternal characteristics in northwest Ethiopia: a retrospective follow-up study.Frontiers in global women's health · 2024Article
- Prediction of postpartum prediabetes by machine learning methods in women with gestational diabetes mellitus.iScience · 2023Article
- Incidence and risk factors of gestational diabetes mellitus in Goba town, Southeast Ethiopia: a prospective cohort study.BMJ open · 2022Article
- Insulin requiring Gestational Diabetes: Risk factors and correlation with postpartum diabetes and prediabetes.Pakistan journal of medical sciencesArticle
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo identify the incidence of postpartum glucose intolerance and develop a prediction model based on antenatal characteristics to predict postpartum glucose intolerance.
designProspective cohort study.
settingGondar town public health facilities in Northwest Ethiopia.
participantsWomen who had gestational diabetes mellitus were advised to undergo postpartum oral glucose tolerance test at 6-12 weeks of delivery. MAIN OUTCOME: Postpartum glucose intolerance. DATA ANALYSIS: Predictors of postpartum glucose intolerance were identified using multivariable logistic regression analysis. The discriminative power of the predictor variables for postpartum glucose intolerance and the model accuracy were computed by area under the receiver operating characteristic curve and estimated by area under the curve (AUC) with 95% CI.
resultsA total of 112 (85.5%) women with gestational diabetes mellitus returned and completed the postpartum oral glucose tolerance test. The incidence of postpartum glucose intolerance was 21.4% (95% CI14.3 to 28.4), inclusive of 18.7% pre-diabetes and 2.7% diabetes. Multivariable logistic regression analysis revealed that advanced maternal age, high fasting plasma glucose level at diagnosis, overweight and/or obesity, and antenatal depression were predictors of postpartum glucose intolerance. The AUC of the final reduced model to predict postpartum glucose intolerance was 0.884 (95% CI 0.822 to 0.937). Fasting plasma glucose at diagnosis of gestational diabetes mellitus (AUC=0.736, 95% CI0.616 to 0.845) and overweight and/or obesity (AUC=0.718, 95% CI 0.614 to 0.814) were better predictors of postpartum glucose intolerance. Moreover, the AUC for the combined predictors of fasting plasma glucose at diagnosis and mid-upper arm circumference was 0.822 (95% CI 0.722 to 0.907), which was the best predictor.
conclusionsThe incidence of postpartum glucose intolerance was high among women with gestational diabetes mellitus. Antenatal predictors modestly predicted postpartum glucose intolerance. The findings suggest ongoing glucose screening is indicated for all women with gestational diabetes mellitus.
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