ArticlePoultry science2020
Graded Eimeria challenge linearly regulated growth performance, dynamic change of gastrointestinal permeability, apparent ileal digestibility, intestinal morphology, and tight junctions of broiler chickens.
Article in Poultry science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
75 citing papers in PubMed, 148 citations in OpenAlex.
- Effect of using mannan-oligosaccharides and β-glucans as feed additives on growth, biochemical parameters, and immunity of Salmonella enterica serovar Enteritidis-challenged turkey.Veterinary research communications · 2026Article
- Dietary Artemisia annua leaf powder modulates intestinal response and cecal microbiota of broiler chickens during peak Eimeria infection.Poultry science · 2026Article
- Article
- Effects of reduced crude protein diets on footpad dermatitis, necrotic enteritis, and coccidiosis in broiler chickens.Poultry science · 2026Review
- Effects of phytogenic feed additive on growth performance, gut health, and antioxidant capacity in broiler chickens challenged with pathogenic Eimeria tenella.Poultry science · 2026Article
- Interactive effects of the feed-borne mycotoxin deoxynivalenol and a mixed-species Eimeria challenge on layer pullets during the transition to lay.Poultry science · 2026Article
- Wheat levels have minor effects on the progression of coccidiosis in turkey poults.Poultry science · 2026Article
- Toll-like receptor-mediated innate immune response correlate with the pathogenicity of Eimeria tenella infection in SPF chickens.Parasites & vectors · 2026Article
- Nutritional strategies to mitigate sub-clinical coccidiosis in Eimeria-challenged broilers.Poultry science · 2026Article
- Factors Affecting Flock Uniformity in Broiler Production: Individual, Environmental, and Management Characteristics.Animals : an open access journal from MDPI · 2026Review
- Architecture, permeability, disruption dynamics and remodeling of tight junction proteins: Implications for performance, health, and welfare of the broiler chicken.Poultry science · 2026Review
- Comparative analysis of jejunal morphology, antioxidant capacity and barrier function between Dahe pigs and Dahe black pigs.Frontiers in veterinary science · 2026Article
- Pathogenic piscine intestinal coccidia infection alters gut microbiome in juvenile Asian seabass (Lates calcarifer).BMC veterinary research · 2025Article
- Dose-dependent contribution of Eimeria tenella to Salmonella infection in broilers: impacts on growth, immunity, and cecal microbiota.Poultry science · 2025Article
- Exploring the interplay betweenThe veterinary quarterly · 2025Review
- Response of broiler chickens to dietary different yeast cell wall components challenged with Salmonella typhimurium.Veterinary research communications · 2025Article
- Additional Valine and Isoleucine Impact Growth Performance, Intestinal Health, and Muscle Growth in Broilers Under Necrotic Enteritis Challenges.Animals : an open access journal from MDPI · 2025Article
- Increasing dietary indigestible protein may exacerbate coccidiosis in broiler chickens.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- Cultivating the endogenous life cycle ofParasitology · 2025Article
- Evaluating Good Husbandry Practices and Organic Fermented Additives for Coccidiosis Control in a Pilot Study Using Slow-Growing Broilers.Animals : an open access journal from MDPI · 2025Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study was conducted to evaluate graded Eimeria challenge on growth performance, apparent ileal digestibility, gastrointestinal permeability, intestinal morphology, gene expression of tight junction protein, and intestinal lesion scores in broiler chickens. There were 5 groups in this study, including a control and 4 different Eimeria treatment doses. A mixed Eimeria spp. solution with 50,000 Eimeria maxima, 50,000 Eimeria tenella, and 250,000 Eimeria acervulina per milliliter was prepared for the high-dose challenge treatment. The 2-fold serial dilution was used to make the medium-high (25,000 E. maxima; 25,000 E. tenella; 125,000 E. acervulina), the medium-low (12,500 E. maxima; 12,500 E. tenella; 62,500 E. acervulina), and the low challenge dose (6,250 E. maxima; 6,250 E. tenella; 31,250 E. acervulina). A total of three hundred sixty 13-day-old male broiler chickens were randomly allocated into 5 treatments with 6 replicated cages. Growth performance was calculated from 0 to 6 D postinfection (DPI). Intestine lesion was scored on 6 DPI. Gastrointestinal permeability was measured on 3, 5, 6, 7, and 9 DPI. The results indicated significant linear reduction in growth performance, intestinal villi height, and ileal nutrient digestibility in response to the increase of Eimeria challenge dose. Furthermore, gene expression of tight junction protein was linearly upregulated by the increasing challenge doses. Significant linear increases of gastrointestinal permeability were found on 5, 6, and 7 DPI (P < 0.01). On 9 DPI, the gastrointestinal permeability was recovered back to normal level in the challenge groups. In conclusion, the higher Eimeria doses birds received, the more severe intestine damage was observed in several gastrointestinal health parameters. The medium-low or medium-high levels of mixed Eimeria oocysts is suggested as an optimum Eimeria-challenge dose to establish a subclinical challenge model for future studies evaluating nutritional strategies. Moreover, it is recommended to measure gastrointestinal permeability on 5 DPI with higher oocysts doses and 6 DPI when using the lower oocysts doses.
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