Evidence map›Paper›PMID 32867963›Full record

ReviewPoultry science2020

Current status of vaccine research, development, and challenges of vaccines for Mycoplasma gallisepticum.

Muhammad Ishfaq, Wanying Hu, Mohammad Zeb Khan, Ijaz Ahmad, Wenxin Guo, Jichang Li

Open access · goldAbstract readReview
In one paragraph

Review in Poultry science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Article
  3. Serological Survey and Initial Control ofPathogens (Basel, Switzerland) · 2026
    Article
  4. Animals : an open access journal from MDPI · 2026
    Article
  5. Assessment of the pathogenicity ofJournal of veterinary research · 2026
    Article
  6. Article
  7. Article
  8. Pathogenic mechanisms and vaccine development forFrontiers in microbiology · 2025
    Review
  9. Article
  10. Article
  11. Immune Evasion ofInternational journal of molecular sciences · 2024
    Review
  12. Article
  13. Article
  14. Detection ofArchives of Razi Institute · 2023
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Muhammad IshfaqHeilongjiang Key Laboratory for Animal Disease Control and Pharmaceutical Development, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, P. R. China.
Wanying HuHeilongjiang Key Laboratory for Animal Disease Control and Pharmaceutical Development, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, P. R. China.
Mohammad Zeb KhanHeilongjiang Key Laboratory for Animal Disease Control and Pharmaceutical Development, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, P. R. China.
Ijaz AhmadDepartment of Animal Health, The University of Agriculture Peshawar, Khyber Pakhtunkhwa 25130, Pakistan.
Wenxin GuoDepartment of Veterinary Drug Residues, Heilongjiang Province Agricultural Products And Veterinary Medicine Feed Technology, Appraisal Station 150030. Electronic address: 1018633122@qq.com.
Jichang LiHeilongjiang Key Laboratory for Animal Disease Control and Pharmaceutical Development, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, P. R. China. Electronic address: lijichang828@sina.com.
Northeast Agricultural University · CNThe University of Agriculture, Peshawar · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycoplasma gallisepticum (MG) is an important avian pathogen that causes significant economic losses in the poultry industry. Surprisingly, the limited protection and adverse reactions caused by the vaccines, including live vaccines, bacterin-based (killed) vaccines, and recombinant viral vaccines is still a major concern. Mycoplasma gallisepticum strains vary in infectivity and virulence and infection may sometimes unapparent and goes undetected. Although extensive research has been carried out on the biology of this pathogen, information is lacking about the type of immune response that confers protection and selection of appropriate protective antigens and adjuvants. Regardless of numerous efforts focused on the development of safe and effective vaccine for the control of MG, the use of modern DNA vaccine technology selected in silico approaches for the use of conserved recombinant proteins may be a better choice for the preparation of novel effective vaccines. More research is needed to characterize and elucidate MG products modulating MG-host interactions. These products could be used as a reference for the preparation and development of vaccines to control MG infections in poultry flocks.

Indexed as

Bacterial VaccinesMycoplasma gallisepticumMycoplasma InfectionsPoultry DiseasesVaccinationAnimalsChickensVeterinary MedicineBacterial Vaccinesattenuated vaccineslive vaccinesMycoplasma gallisepticumnew approachesvaccine

Identifiers

PMID32867963
PMCPMC7598112
OpenAlexW3038105299

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.