ArticleCritical care (London, England)2020
Body-mass index and long-term risk of sepsis-related mortality: a population-based cohort study of 0.5 million Chinese adults.
Article in Critical care (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Exploring the relationship between life course adiposity and sepsis: insights from a two-sample Mendelian randomization analysis.Frontiers in endocrinology · 2024Pooled it
- A nomogram to predict prolonged stay of obesity patients with sepsis in ICU: Relevancy for predictive, personalized, preventive, and participatory healthcare strategies.Frontiers in public health · 2022Trial
- CT-adipose measures identify severe SARS-CoV-2 risk beyond traditional obesity metrics: a C4R cohort study.BMC pulmonary medicine · 2026Article
- Preoperative machine learning algorithm for predicting urosepsis after percutaneous nephrolithotomy using EMR data.Urolithiasis · 2025Article
- Advanced lung cancer inflammation index and all-cause mortality in critically ill patients with sepsis: analysis of the MIMIC-IV database.BMC infectious diseases · 2025Observational
- Association of Modifiable Lifestyle and Metabolic Factors With the Risk of Developing Sepsis: 2-Sample Mendelian Randomized Study.Interactive journal of medical research · 2025Article
- Disparities, trends, and projections of cancer mortality burden related to high body mass index in China from 2005 to 2030.Cell reports. Medicine · 2025Article
- Causality of genetically predicted solid cancers on risk of sepsis: insights from Mendelian randomization.Discover oncology · 2025Article
- Association between complementary anthropometric measures and all-cause mortality risk in adults: NHANES 2011-2016.European journal of clinical nutrition · 2025Article
- Association of body mass index changes with short-term mortality risks in ICU patients with sepsis across different admission BMI states: analysis of the MIMIC-IV database.Frontiers in immunology · 2025Article
- Impact of unintentional weight loss on 30-day mortality in intensive care unit sepsis patients: a retrospective cohort study.Scientific reports · 2024Article
- Article
- The Association of Body Mass Index and Waist Circumference with Sepsis-Related Mortality in South Korea.Diagnostics (Basel, Switzerland) · 2024Article
- Correlation between body mass index and gender-specific 28-day mortality in patients with sepsis: a retrospective cohort study.Frontiers in medicine · 2024Article
- Association of obesity and mortality in sepsis patients: A meta-analysis from observational evidence.Heliyon · 2023Article
- Temporal trends of sepsis-related mortality in China, 2006-2020: a population-based study.Annals of intensive care · 2023Article
- Safety and Efficacy of Excimer Laser Powered Lead Extractions in Obese Patients: A GALLERY Subgroup Analysis.Journal of clinical medicine · 2023Article
- National incidence and mortality of hospitalized sepsis in China.Critical care (London, England) · 2023Article
- Obesity Paradox in Lung Diseases: What Explains It?Obesity facts · 2023Review
- Preclinical Mouse Models in Sepsis: Don't Throw the Baby Out with the Bathwater [Response to Letter].Journal of inflammation research · 2023Article
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
backgroundSepsis represents a major worldwide healthcare burden. However, how body-mass index (BMI) is related to the long-term risk of sepsis-related mortality in low- and middle-income countries remains uncertain.
methodsWe examined the associations of sepsis-related mortality with both baseline BMI and waist circumference (WC) using data from China Kadoorie Biobank, a prospective cohort recruited during 2004-2008 and followed up to December 2016. After excluding participants with chronic obstructive pulmonary disease, tuberculosis, cancer, heart disease, and stroke, and omitting the first 3 years of follow-up, 440,763 participants remained for analysis.
resultsDuring a median follow-up of 10.0 years, 1957 sepsis-related deaths (3,134,870 person-years) were included for analysis. Compared with reference BMI of 22.5 to < 25.0 kg/m
conclusionsUnderweight, lower normal weight, and abdominal obesity are associated with increased future risk of sepsis-related mortality over 10 years in the Chinese population. The double burden of underweight and obesity indicates a heavy sepsis burden faced by low- and middle-income countries.
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