ArticleBMC medicine2020
Severe nausea and vomiting in pregnancy: psychiatric and cognitive problems and brain structure in children.
Article in BMC medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Multi-ancestry genome-wide association study of severe pregnancy nausea and vomiting.Nature genetics · 2026Pooled it
- A Systematic Patent Review (2008-2023) for Treatment in Pregnancy.Current medicinal chemistry · 2024Pooled it
- Ottawa nutritional guide intervention for nausea and vomiting in pregnancy: a randomized controlled trial protocol.Reproductive health · 2025Article
- Linking pregnancy- and birth-related risk factors to a multivariate fusion of child cortical structure.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Linking Pregnancy- and Birth-Related Risk Factors to a Multivariate Fusion of Child Cortical Structure.bioRxiv : the preprint server for biology · 2025Article
- Longitudinal Sex-at-Birth and Age Analyses of Cortical Structure in the ABCD Study.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Multi-ancestry GWAS of severe pregnancy nausea and vomiting identifies risk loci associated with appetite, insulin signaling, and brain plasticity.Research square · 2024Article
- Multi-ancestry GWAS of severe pregnancy nausea and vomiting identifies risk loci associated with appetite, insulin signaling, and brain plasticity.medRxiv : the preprint server for health sciences · 2024Article
- Hyperemesis gravidarum and the risk of offspring morbidity: a longitudinal cohort study.European journal of pediatrics · 2024Article
- Nausea and vomiting in pregnancy (NVP) in Chinese pregnant women: a cross-sectional study.BMC pregnancy and childbirth · 2024Article
- Re-examining the adaptive function of nausea and vomiting in pregnancy.Evolution, medicine, and public health · 2024Article
- Lower gestational age is associated with lower cortical volume and cognitive and educational performance in adolescence.BMC medicine · 2022Article
- Brain functional connectivities that mediate the association between childhood traumatic events, and adult mental health and cognition.EBioMedicine · 2022Article
- Patterns of Use and Self-reported Effectiveness of Cannabis for Hyperemesis Gravidarum.Geburtshilfe und Frauenheilkunde · 2022Article
- Review
- The orbitofrontal cortex: reward, emotion and depression.Brain communications · 2020Review
- Mirtazapine for Severe Nausea and Vomiting During Pregnancy: Case Presentations and Recommendations.Journal of clinical psychopharmacologyArticle
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
Abstract
backgroundTwo studies have suggested that severe prolonged nausea and vomiting during pregnancy is associated with emotional and behavioral problems in offspring, with smaller sample size and short-term follow-up. Moreover, little information is available on the role of the brain structure in the associations.
methodsIn a US-based cohort, the association was investigated between severe prolonged nausea and vomiting in pregnancy (extending after the second trimester and termed SNVP), psychiatric and cognitive problems, and brain morphology, from the Adolescent Brain Cognitive Development (ABCD) study, from 10,710 children aged 9-11 years. We validated the emotional including psychiatric findings using the Danish National Cohort Study with 2,092,897 participants.
resultsSNVP was significantly associated with emotional and psychiatric problems (t = 8.89, Cohen's d = 0.172, p = 6.9 × 10
conclusionsSNVP is strongly associated with psychiatric and cognitive problems in children, with mediation by brain structure. These associations highlight the clinical importance and potential benefits of the treatment of SNVP, which could reduce the risk of psychiatric disorder in the next generation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.