Evidence map›Paper›PMID 32867765›Full record

Observational studyRespiratory research2020

A retrospective analysis of usefulness of impulse oscillometry system in the treatment of asthma.

Hiroyuki Sugawara, Atsushi Saito, Saori Yokoyama, Kazunori Tsunematsu, Hirofumi Chiba, Hiroki Takahashi

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Respiratory research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Association between annual change in FEVBMC pulmonary medicine · 2022
    Article
  11. Clinical significance and applications of oscillometry.European respiratory review : an official journal of the European Respiratory Society · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hiroyuki SugawaraSugawara Internal Medicine and Respiratory Clinic, Tomakomai, 053-0821, Japan.
Atsushi SaitoDepartment of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, S1W16 Chuoku, Sapporo, Hokkaido, 060-8543, Japan. a-saito@sapmed.ac.jp.ORCID http://orcid.org/0000-0003-3430-884X
Saori YokoyamaDepartment of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, S1W16 Chuoku, Sapporo, Hokkaido, 060-8543, Japan.
Kazunori TsunematsuSugawara Internal Medicine and Respiratory Clinic, Tomakomai, 053-0821, Japan.
Hirofumi ChibaDepartment of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, S1W16 Chuoku, Sapporo, Hokkaido, 060-8543, Japan.
Hiroki TakahashiDepartment of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, S1W16 Chuoku, Sapporo, Hokkaido, 060-8543, Japan.
Sapporo Medical University · JPNational Institute of Technology, Tomakomai College · JP

Funding

Japan Society for the Promotion of Science 19K23610NOVARTIS Foundation (Japan) for the Promotion of Science None
6 · The paper itself

Abstract

backgroundBronchial asthma (BA) has different phenotypes, and it requires a clinically effective subtype classification system. The impulse oscillometry system (IOS) is an emerging technique device used in respiratory functional tests. However, its efficacy has not been validated. Therefore, this study aimed to assess the relationship between BA and the IOS parameters, and the difference in the therapeutic effects of inhaled corticosteroids (ICSs) among the subtype classifications was evaluated using the IOS.

methodsOf the 245 patients with bronchial asthma who were screened, 108 were enrolled in this study. These patients were divided based on three subtypes according to the IOS result as follows: central predominant type (n = 34), peripheral predominant type (n = 58), and resistless type (n = 16). Then, the following ICSs were randomly prescribed in daily medical care: coarse-particle ICS (fluticasone propionate [FP]), fine-particle ICS (mometasone furoate [MF]), and moderate-particle ICS (budesonide [BUD]). The treatment effects were assessed using the Asthma Health Questionnaire (AHQ) and the Asthma Control Test (ACT) and were compared among the three subtypes.

resultsIn the central predominant type, the AHQ score of the MF group was significantly higher than that of the FP group (15.4 vs. 3.6, p < 0.01) and the BUD group (15.4 vs. 8.8, p < 0.05); the ACT score of the FP group was significantly higher than that of the MF and BUD groups (24.3 vs. 21.7, 22.3, respectively, p < 0.05) at 4 weeks after treatment. In the peripheral predominant type, the AHQ score of the FP group was significantly higher than that of the MF group (14.1 vs. 3.4, p < 0.05); the ACT score of the FP group was lower than that of the MF and BUD groups (22.8 vs. 24.6, 24.4, respectively, p < 0.01) at 4 weeks after treatment.

conclusionsAn association was observed between IOS subtype classification and ICS particle size in terms of therapeutic efficacy in BA. This result indicates that the IOS could be an effective tool in the selection of ICS and the evaluation of the BA phenotype.

Indexed as

AdultAsthmaFemaleFollow-Up StudiesForced Expiratory VolumeHumansMaleMiddle AgedOscillometryRetrospective StudiesTreatment OutcomeAsthma control testAsthma health questionnaireBronchial asthmaImpulse oscillometry systemInhaled corticosteroidsPulmonary function test

Identifiers

PMID32867765
PMCPMC7457354
OpenAlexW3082591602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.