SynthesisBMC nephrology2020
Risk factors for mortality in elderly haemodialysis patients: a systematic review and meta-analysis.
Synthesis in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 7 syntheses or guidelines pooled it, 76 citations in OpenAlex.
- Association Between Frailty and Mortality, Falls and Hospitalisation Among Patients Undergoing Dialysis: A Systematic Review and Meta-Analysis.Nursing open · 2025Pooled it
- Global prevalence of frailty in hemodialysis patients: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Impact of the geriatric nutritional risk index on long-term outcomes in patients undergoing hemodialysis: a meta-analysis of observational studies.Frontiers in nutrition · 2024Pooled it
- Prevalence of cognitive impairment and its predictors among chronic kidney disease patients: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Interventions to reduce falls among dialysis patients: a systematic review.BMC nephrology · 2023Pooled it
- Outcomes of peritoneal dialysis in elderly vs non-elderly patients: A systemic review and meta-analysis.PloS one · 2022Pooled it
- Prevalence and Associated Factors of Frailty and Mortality in Patients with End-Stage Renal Disease Undergoing Hemodialysis: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2021Pooled it
- Ankle-brachial index rather than brachial-ankle pulse wave velocity is associated with cognitive function in older adults undergoing incident hemodialysis: a multicentre cross-sectional study.Annals of medicine · 2026Article
- Incremental peritoneal dialysis preserves residual renal function in diabetic end-stage kidney disease.Renal failure · 2026Article
- ABO Blood Types and Mortality in Patients Undergoing Hemodialysis.Kidney international reports · 2026Article
- Effects of nursing facility residency on mortality in patients initiating hemodialysis: a retrospective cohort study.BMC geriatrics · 2026Article
- Factors associated with survival among patients with end-stage kidney disease undergoing hemodialysis in Tanzania: a cohort study.BMC nephrology · 2026Article
- Cardiovascular Mortality and Its Risk Factors in Patients on Twice-Weekly Maintenance Hemodialysis: An 18-Month Retrospective Cohort Study from a Tertiary Center in Indonesia.International journal of nephrology and renovascular disease · 2026Article
- Teledialysis in Community Settings: Evaluation of Feasibility, Safety and Effectiveness.International journal of telemedicine and applications · 2026Article
- Referral patterns in the CKD.QLD Registry: A call for revisiting the definition of late referral.PloS one · 2026Article
- Analysis of arteriovenous fistula failure factors and construction of nomogram prediction model in patients with maintenance hemodialysis.Renal failure · 2025Article
- Analysis of the trajectory of cognitive function changes and influencing factors in maintenance hemodialysis patients: a prospective longitudinal study.Renal failure · 2025Article
- Effects of hospitalization before hemodialysis on mortality in dialysis patients.BMC geriatrics · 2025Article
- Evaluating tissue plasminogen activator (tPA) in dialysis catheter dysfunction: A focus on fibrin sheath and risk factors.American heart journal plus : cardiology research and practice · 2025Article
- Risk factors for unexpected clinical deterioration in hospitalized patients undergoing maintenance hemodialysis.Clinical and experimental nephrology · 2025Observational
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundOlder haemodialysis patients accompany a high burden of functional impairment, limited life expectancy, and healthcare utilization. This meta-analysis aimed to evaluate how various risk factors influenced the prognosis of haemodialysis patients in late life, which might contribute to decision making by patients and care providers.
methodsPubMed, Embase, and Cochrane Central were searched systematically for studies evaluating the risk factors for mortality in elderly haemodialysis patients. Twenty-eight studies were included in the present systematic review. The factors included age, cardiovascular disease, diabetes mellitus, type of vascular access, dialysis initiation time, nutritional status and geriatric impairments. Geriatric impairments included frailty, cognitive or functional impairment and falls. Relative risks with 95% confidence intervals were derived.
resultsFunctional impairment (OR = 1.45, 95% CI: 1.20-1.75), cognitive impairment (OR = 1.46, 95% CI: 1.32-1.62) and falls (OR = 1.14, 95% CI: 1.06-1.23) were significantly and independently associated with increased mortality in elderly haemodialysis patients. Low body mass index conferred a mortality risk (OR = 1.43, 95% CI: 1.31-1.56) paralleling that of frailty as a marker of early death. The results also confirmed that the older (OR = 1.43, 95% CI: 1.22-1.68) and sicker (in terms of Charlson comorbidity index) (OR = 1.41, 95% CI: 1.35-1.50) elderly haemodialysis patients were, the more likely they were to die. In addition, increased mortality was associated with early-start dialysis (OR = 1.18, 95% CI: 1.01-1.37) and with the use of a central venous catheter (OR = 1.53, 95% CI: 1.44-1.62).
conclusionsMultiple factors influence the risk of mortality in elderly patients undergoing haemodialysis. Geriatric impairment is related to poor outcome. Functional/cognitive impairment and falls in elderly dialysis patients are strongly and independently associated with mortality.
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