Evidence map›Paper›PMID 32867717›Full record

ArticleBMC neurology2020

Neurolisteriosis in a previously asymptomatic patient with serum IgM deficiency: a case report.

Kostas Patas, Theodoros Mavridis, Katerina Psarra, Vassilis E Papadopoulos, Georgia Mandilara, Alexandra Tsirogianni, Sophia Vassilopoulou, Stylianos Chatzipanagiotou

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In one paragraph

Article in BMC neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kostas PatasDepartment of Medical Biopathology, Eginition Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
Theodoros MavridisDepartment of Neurology, Eginition Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
Katerina PsarraDepartment of Immunology and Histocompatibility, Evangelismos General Hospital, Athens, Greece.
Vassilis E PapadopoulosDepartment of Neurology, Eginition Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
Georgia MandilaraNational School of Public Health & Central Public Health Laboratory, Hellenic Centre of Disease Control and Prevention, Vari, Greece.
Alexandra TsirogianniDepartment of Immunology and Histocompatibility, Evangelismos General Hospital, Athens, Greece.
Sophia VassilopoulouDepartment of Neurology, Eginition Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
Stylianos ChatzipanagiotouDepartment of Medical Biopathology, Eginition Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece. schatzi@med.uoa.gr.ORCID http://orcid.org/0000-0002-1251-8355
National and Kapodistrian University of Athens · GREvangelismos Hospital · GRNational School of Public Health · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundListeria monocytogenes is an opportunistic pathogen of the central nervous system commonly associated with impaired cell-mediated immunity. We hereby present a case of adult neurolisteriosis where the only immunological feature persistently present was serum IgM deficiency, suggesting that non-specific humoral immunity may also play a central role in the control of neuroinvasion by Listeria monocytogenes. CASE PRESENTATION: A 62-year-old male who had never experienced severe infections presented with headache, nuchal rigidity and confusion. Neuroimaging was normal and lumbar puncture revealed pleiocytosis (760 leukocytes/mm

conclusionsAs far as we know, this is the first reported case of neurolisteriosis associated with IgM deficiency in an adult individual without a history of severe infections or other underlying conditions. A possible role of circulating IgM against invasive disease caused by Listeria monocytogenes, particularly in the early course of host-pathogen interaction, is discussed.

Indexed as

Immunocompromised HostHumansImmunoglobulin MImmunologic Deficiency SyndromesMaleMeningitis, ListeriaMiddle AgedImmunoglobulin MIgM deficiencyListeria monocytogenesNeurolisteriosis

Identifiers

PMID32867717
PMCPMC7457472
OpenAlexW3082867002

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.