ArticleBMC neurology2020
Characteristics of cognitive impairment in adult asymptomatic moyamoya disease.
Article in BMC neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 39 citations in OpenAlex.
- Remote ischemic conditioning prevents ischemic cerebrovascular events in children with moyamoya disease: a randomized controlled trial.World journal of pediatrics : WJP · 2024Trial
- Treatment Options for Patients With Moyamoya Disease: A Retrospective Cohort Study.Revista de neurologia · 2025Article
- Multisystemic Impact of RNF213 Arg4810Lys: A Comprehensive Review of Moyamoya Disease and Associated Vasculopathies.International journal of molecular sciences · 2025Review
- Cognitive characteristics and ischemic prognosis of quantitative white matter hyperintensities in adult moyamoya disease.Communications medicine · 2025Article
- Disrupted resting-state interhemispheric functional connectivity in patients with first-episode moyamoya disease.Scientific reports · 2025Article
- The cerebellar glucose metabolism in moyamoya vasculopathy and its correlation with neurocognitive performance after cerebral revascularization surgery: a [European journal of nuclear medicine and molecular imaging · 2025Article
- Non-Invasive Diagnosis of Moyamoya Disease Using Serum Metabolic Fingerprints and Machine Learning.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Research progress of artificial intelligence in moyamoya disease.Frontiers in neurology · 2025Review
- Neuropsychiatric Symptoms of Moyamoya Disease: Considerations for the Clinician.Neuropsychiatric disease and treatment · 2024Review
- Cognitive dysfunction in Moyamoya disease: latest developments and future directions.Frontiers in human neuroscience · 2024Review
- Association between DIAPH1 variant and posterior circulation involvement with Moyamoya disease.Scientific reports · 2023Article
- Association of cognitive function and hypoperfusion in Moyamoya disease patients without stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Article
- Association between White Matter Hyperintensities Burden and Cognitive Function in Adult Asymptomatic Moyamoya Disease.Journal of clinical medicine · 2023Article
- Effect of cerebral oxygen saturation monitoring in patients undergoing superficial temporal anterior-middle cerebral artery anastomosis for ischemic Moyamoya disease: a prospective cohort study.Frontiers in neurology · 2023Article
- Current Understanding of Moyamoya Disease (MMD) and Associated Neuropsychiatric Outcomes.Neuropsychiatric disease and treatment · 2023Review
- Cognitive Impairment in Primary and Secondary Headache Disorders.Current pain and headache reports · 2022Review
- Thalamic structure and anastomosis in different hemispheres of moyamoya disease.Frontiers in neuroscience · 2022Article
- Altered functional connectivity is related to impaired cognition in left unilateral asymptomatic carotid artery stenosis patients.BMC neurology · 2021Article
- Silent Moyamoya disease - A rare case report.Radiology case reports · 2021Article
- Impairments in brain perfusion, executive control network, topological characteristics, and neurocognition in adult patients with asymptomatic Moyamoya disease.BMC neuroscience · 2021Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundCognitive impairment in adult moyamoya disease (MMD) is thought to be the result of ischemic stroke; however, the presence and extent of cognitive decline in asymptomatic patients is unclear.
methodsAfter classification using T2-weighted fluid attenuated inversion recovery (FLAIR) magnetic resonance imaging (MRI), a total of 19 MMD patients with a history of cerebral infarction, 21 asymptomatic MMD patients, and 20 healthy controls matched for age, sex, and years of education were prospectively included in this study. A detailed neuropsychological evaluation of two moyamoya subgroups and normal controls was conducted.
resultsAsymptomatic patients showed varying degrees of decline in intelligence (Raven's Standard Progressive Matrices, P = 0.001), spatial imagination (mental rotation, P = 0.014), working memory (verbal working memory-backward digit span, P = 0.011), and computational ability (simple subtraction, P = 0.014; complex subtraction, P < 0.001) compared with normal controls. MMD patients with cerebral infarction had more severe impairment in complex arithmetic (P = 0.027) and word short-term memory (P = 0.01) than those without symptoms.
conclusionIn asymptomatic MMD patients, a variety of cognitive impairment precedes the onset of clinical symptoms such as cerebral infarction, which may be a long-term complication of conservative treatment.
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