Evidence map›Paper›PMID 32867656›Full record

ReviewCurrent radiopharmaceuticals2021

Cyclotron Production of PET Radiometals in Liquid Targets: Aspects and Prospects.

Mukesh K Pandey, Timothy R DeGrado

Open access · greenAbstract readReview
In one paragraph

Review in Current radiopharmaceuticals, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Pressed Solid Target Production ofCurrent radiopharmaceuticals · 2025
    Article
  6. Optimised production of technetium-94m for PET imaging by proton-irradiation of phosphomolybdic acid in cyclotron liquid target.Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine · 2024
    Article
  7. Review
  8. Recovery of Gallium-68 and Zinc from HNOMolecules (Basel, Switzerland) · 2022
    Article
  9. Evaluation of differentScientific reports · 2022
    Article
  10. Production Review of Accelerator-Based Medical Isotopes.Molecules (Basel, Switzerland) · 2022
    Review
  11. Article
  12. Article
  13. A new solid target design for the production ofAmerican journal of nuclear medicine and molecular imaging · 2022
    Article
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mukesh K PandeyDivision of Nuclear Medicine, Department of Radiology, Mayo Clinic Rochester, Minneapolis, 55905, United States.
Timothy R DeGradoDivision of Nuclear Medicine, Department of Radiology, Mayo Clinic Rochester, Minneapolis, 55905, United States.
Mayo Clinic · US

Funding

THE PGRN/TDP-43 AXIS IN ALZHEIMER?S DISEASE AND NEURODEGENERATIONP50AG016574 · NIA · MAYO CLINIC ROCHESTER · PI PETERSEN, RONALD C · 1999 to 2018
$36.9M
Department of Energy (DOE) USA DESC-0008947NIA NIH HHS P50 AG016574The National Institute on Aging (NIA) USA AG16574
6 · The paper itself

Abstract

The present review describes the methodological aspects and prospects of the production of Positron Emission Tomography (PET) radiometals in a liquid target using low-medium energy medical cyclotrons. The main objective of this review is to delineate and discuss the critical factors involved in the liquid target production of radiometals, including type of salt solution, solution composition, beam energy, beam current, the effect of irradiation duration (length of irradiation) and challenges posed by in-target chemistry in relation with irradiation parameters. We also summarize the optimal parameters for the production of various radiometals in liquid targets. Additionally, we discuss the future prospects of PET radiometals production in the liquid targets for academic research and clinical applications. Significant emphasis has been given to the production of

Indexed as

CyclotronsPositron-Emission TomographyGallium RadioisotopesRadiochemistryRadioisotopesRadiopharmaceuticalsYttrium RadioisotopesZinc RadioisotopesZirconiumGallium-68Gallium RadioisotopesRadioisotopesRadiopharmaceuticalsYttrium-86Yttrium RadioisotopesZinc-63Zinc RadioisotopesZirconiumZirconium-8963Zn and 89Zr.68Ga86YcyclotronLiquid targetradiometalssolution target

Identifiers

PMID32867656
PMCPMC9909776
OpenAlexW3081312239

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.