Evidence map›Paper›PMID 32867402›Full record

ArticleMolecules (Basel, Switzerland)2020

Synthesis and Antiplasmodial Evaluation of 4-Carboxamido- and 4-Alkoxy-2-Trichloromethyl Quinazolines.

Dyhia Amrane, Armand Gellis, Sébastien Hutter, Marion Prieri, Pierre Verhaeghe, Nadine Azas, Patrice Vanelle, Nicolas Primas

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Novel 2-Sulfanylquinazolin-4(3Molecules (Basel, Switzerland) · 2023
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Dyhia AmraneEquipe Pharmaco-Chimie Radicalaire, Faculté de Pharmacie, Aix Marseille Univ, CNRS, ICR UMR 7273, 13385 Marseille CEDEX 05, France.
Armand GellisEquipe Pharmaco-Chimie Radicalaire, Faculté de Pharmacie, Aix Marseille Univ, CNRS, ICR UMR 7273, 13385 Marseille CEDEX 05, France.
Sébastien HutterIHU Méditerranée Infection, UMR VITROME, IRD, SSA, Mycology & Tropical Eucaryotic Pathogens, Aix Marseille Univ, 13005 Marseille CEDEX 05, France.
Marion PrieriEquipe Pharmaco-Chimie Radicalaire, Faculté de Pharmacie, Aix Marseille Univ, CNRS, ICR UMR 7273, 13385 Marseille CEDEX 05, France.ORCID 0000-0003-3613-9752
Pierre VerhaegheLCC-CNRS Université de Toulouse, CNRS, UPS, 31400 Toulouse, France.ORCID 0000-0003-0238-2447
Nadine AzasIHU Méditerranée Infection, UMR VITROME, IRD, SSA, Mycology & Tropical Eucaryotic Pathogens, Aix Marseille Univ, 13005 Marseille CEDEX 05, France.
Patrice VanelleEquipe Pharmaco-Chimie Radicalaire, Faculté de Pharmacie, Aix Marseille Univ, CNRS, ICR UMR 7273, 13385 Marseille CEDEX 05, France.
Nicolas PrimasEquipe Pharmaco-Chimie Radicalaire, Faculté de Pharmacie, Aix Marseille Univ, CNRS, ICR UMR 7273, 13385 Marseille CEDEX 05, France.
Centre National de la Recherche Scientifique · FRMéditerranée Infection Foundation · FR

Funding

Agence Nationale de la Recherche ANR-17-CE11-0017
6 · The paper itself

Abstract

From three previously identified antiplasmodial hit compounds (

Indexed as

AntimalarialsQuinazolinesHep G2 CellsHumansPlasmodium falciparumStructure-Activity RelationshipAntimalarialsQuinazolines2-trichloromethylquinazolinein vitro HepG2 cytotoxicityPlasmodium falciparumstructure-activity relationships

Identifiers

PMID32867402
PMCPMC7504092
OpenAlexW3080704248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.