Evidence map›Paper›PMID 32867384›Full record

ArticleInternational journal of molecular sciences2020

A Novel Peptide Antibiotic, Pro10-1D, Designed from Insect Defensin Shows Antibacterial and Anti-Inflammatory Activities in Sepsis Models.

Manigandan Krishnan, Joonhyeok Choi, Ahjin Jang, Yangmee Kim

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 40 citations in OpenAlex.

  1. Phospholipid-Coated FeAntibiotics (Basel, Switzerland) · 2026
    Article
  2. Advances of Antimicrobial Peptides in the Treatment of Multidrug-Resistant Bacteria.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Protective Effects of Rhamnetin in Carbapenem-ResistantInternational journal of molecular sciences · 2023
    Article
  8. Review
  9. Article
  10. Creation of New Antimicrobial Peptides.International journal of molecular sciences · 2023
    Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Antiseptic 9-Meric Peptide with Potency against Carbapenem-ResistantInternational journal of molecular sciences · 2021
    Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Manigandan KrishnanDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea.
Joonhyeok ChoiDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea.
Ahjin JangDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea.
Yangmee KimDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea.ORCID 0000-0001-6438-4718
Konkuk University · KR

Funding

National Research Foundation of Korea 2020R1A2C2005338.
6 · The paper itself

Abstract

Owing to the challenges faced by conventional therapeutics, novel peptide antibiotics against multidrug-resistant (MDR) gram-negative bacteria need to be urgently developed. We had previously designed Pro9-3 and Pro9-3D from the defensin of beetle

Indexed as

Acinetobacter baumanniiAnimalsAntimicrobial Cationic PeptidesCell MembraneColeopteraDefensinsDisease Models, AnimalDrug Resistance, Multiple, BacterialDrug StabilityEscherichia coliEscherichia coli InfectionsFemaleInsect ProteinsLipopolysaccharidesMiceMicrobial Sensitivity TestsAntimicrobial Cationic PeptidesDefensinsInsect ProteinsLipopolysaccharidesNF-kappa BTlr4 protein, mouseToll-Like Receptor 4antimicrobial peptidebiofilmgram-negative infectionpeptide antibioticssepsis

Identifiers

PMID32867384
PMCPMC7504360
OpenAlexW3081497335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.