Evidence map›Paper›PMID 32867358›Full record

ArticleMolecules (Basel, Switzerland)2020

Automated Synthesis of Fluorine-18 Labeled CXCR4 Ligand via the Conjugation with Nicotinic Acid

Falguni Basuli, Xiang Zhang, Tim E Phelps, Elaine M Jagoda, Peter L Choyke, Rolf E Swenson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. One-Step Synthesis of [ACS central science · 2024
    Article
  2. Article
  3. Article
  4. [Molecules (Basel, Switzerland) · 2023
    Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Falguni BasuliChemistry and Synthesis Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Rockville, MD 20892, USA.
Xiang ZhangChemistry and Synthesis Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Rockville, MD 20892, USA.
Tim E PhelpsMolecular Imaging Program, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Elaine M JagodaMolecular Imaging Program, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Peter L ChoykeMolecular Imaging Program, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Rolf E SwensonChemistry and Synthesis Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Rockville, MD 20892, USA.
National Institutes of Health · USNational Cancer Institute · USNational Heart Lung and Blood Institute · US

Funding

NCI NIH HHS HHSN261200800001E
6 · The paper itself

Abstract

The C-X-C motif chemokine receptor 4 (CXCR4) is a seven-transmembrane G protein-coupled receptor that is overexpressed in numerous diseases, particularly in various cancers and is a powerful chemokine, attracting cells to the bone marrow niche. Therefore, CXCR4 is an attractive target for imaging and therapeutic purposes. The goal of this study is to develop an efficient, reproducible, and straightforward method to prepare a fluorine-18 labeled CXCR4 ligand. 6-[

Indexed as

RadiopharmaceuticalsReceptors, CXCR4EstersFluorine RadioisotopesHeLa CellsHumansLigandsNeoplasmsSuccinimidesCXCR4 protein, humanEstersFluorine-18Fluorine RadioisotopesLigandsN-hydroxysuccinimideRadiopharmaceuticalsReceptors, CXCR4SuccinimidesCXCR4fluorination on the Sep-Pakfluorine-18SFPyT140

Identifiers

PMID32867358
PMCPMC7504725
OpenAlexW3080165735

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.