Evidence map›Paper›PMID 32867307›Full record

ReviewInternational journal of molecular sciences2020

MmpL3 Inhibition: A New Approach to Treat Nontuberculous Mycobacterial Infections.

Jigar P Sethiya, Melanie A Sowards, Mary Jackson, Elton Jeffrey North

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Unlocking Opportunities forACS infectious diseases · 2024
    Review
  7. The progress ofFrontiers in medicine · 2024
    Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. OvercomingActa pharmaceutica Sinica. B · 2022
    Review
  15. The Antimalarial Mefloquine Shows Activity againstInternational journal of molecular sciences · 2021
    Article
  16. Review
  17. Microorganisms · 2021
    Article
  18. Rufomycin Exhibits Dual Effects AgainstFrontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jigar P SethiyaDepartment of Pharmacy Sciences, School of Pharmacy & Health Professions, Creighton University, Omaha, NE 68178, USA.
Melanie A SowardsDepartment of Pharmacy Sciences, School of Pharmacy & Health Professions, Creighton University, Omaha, NE 68178, USA.
Mary JacksonMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA.
Elton Jeffrey NorthDepartment of Pharmacy Sciences, School of Pharmacy & Health Professions, Creighton University, Omaha, NE 68178, USA.
Creighton University · USColorado State University · US

Funding

MmpL3 as a target for novel anti-TB agentsR01AI116525 · NIAID · COLORADO STATE UNIVERSITY · PI JACKSON, MARY · 2015 to 2024
$5.3M
Cystic Fibrosis Foundation NORTH18I0 (Pilot & Feasibility Award)NIAID NIH HHS R01 AI116525NIH HHS AI116525
6 · The paper itself

Abstract

Outside of

Indexed as

Anti-Bacterial AgentsBacterial ProteinsBiological TransportDrug DiscoveryDrug Resistance, Multiple, BacterialGene Expression Regulation, BacterialHumansIodophorsIsoxazolesMembrane Transport ProteinsMycobacterium Infections, NontuberculousMycolic AcidsNontuberculous MycobacteriaPolysaccharidesSpiro CompoundsAnti-Bacterial AgentsBacterial ProteinsIodophorsIsoxazolesMembrane Transport ProteinsMycolic Acidspharmaceutical FS-1PolysaccharidesSMARt-420Spiro CompoundsMmpL3Mycobacterium abscessusmycolic acidnontuberculous mycobacteriasusceptibility reversion

Identifiers

PMID32867307
PMCPMC7503588
OpenAlexW3080966514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.