ReviewPharmaceutics2020
Nanotechnology-Based Medical Devices for the Treatment of Chronic Skin Lesions: From Research to the Clinic.
Review in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Biopolymer-Based Hydrogels for Wound Healing: Advances in Cellulose, Chitosan, Alginate, and Hyaluronic Acid from Design to Clinical Translation.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Anti-Inflammatory and Antimicrobial Effect of Ellagic Acid and Punicalagin in Dermal Fibroblasts.International journal of molecular sciences · 2025Article
- Assessing particle count in electron microscopy measurements of nanomaterials to support regulatory guidance.Scientific reports · 2025Article
- Nanotechnology-based biomedical devices in the cancer diagnostics and therapy.Medical oncology (Northwood, London, England) · 2025Review
- Smart copper-doped clays in biomimetic microparticles for wound healing and infection control.Materials today. Bio · 2024Article
- Nanotechnology development in surgical applications: recent trends and developments.European journal of medical research · 2023Review
- Advances in tissue engineering and biofabrication forBioprinting (Amsterdam, Netherlands) · 2023Article
- How to Promote Skin Repair? In-Depth Look at Pharmaceutical and Cosmetic Strategies.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Design of Novel Mechanically Resistant and Biodegradable Multichannel Platforms for the Treatment of Peripheral Nerve Injuries.Biomacromolecules · 2023Article
- Sustainable Nanomaterials for Biomedical Applications.Pharmaceutics · 2023Review
- Extracellular vesicles modulate key signalling pathways in refractory wound healing.Burns & trauma · 2023Review
- Mycelium-based biomaterials as smart devices for skin wound healing.Frontiers in bioengineering and biotechnology · 2023Article
- Smart nano-in-microparticles to tackle bacterial infections in skin tissue engineering.Materials today. Bio · 2022Article
- Isolation ofPharmaceutics · 2022Article
- Inorganic Nanomaterials in Tissue Engineering.Pharmaceutics · 2022Review
- Promotive effects of four herbal medicine ARCC on wound healing in mice and human.Health science reports · 2022Article
- Membranous Extracellular Matrix-Based Scaffolds for Skin Wound Healing.Pharmaceutics · 2021Review
- Experimental Study on Wound Area Measurement with Mobile Devices.Sensors (Basel, Switzerland) · 2021Article
- Electrospun Scaffolds in Periodontal Wound Healing.Polymers · 2021Article
- Innovative Strategies in Tendon Tissue Engineering.Pharmaceutics · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Chronic wounds, such as pressure ulcers, diabetic ulcers, venous ulcers and arterial insufficiency ulcers, are lesions that fail to proceed through the normal healing process within a period of 12 weeks. The treatment of skin chronic wounds still represents a great challenge. Wound medical devices (MDs) range from conventional and advanced dressings, up to skin grafts, but none of these are generally recognized as a gold standard. Based on recent developments, this paper reviews nanotechnology-based medical devices intended as skin substitutes. In particular, nanofibrous scaffolds are promising platforms for wound healing, especially due to their similarity to the extracellular matrix (ECM) and their capability to promote cell adhesion and proliferation, and to restore skin integrity, when grafted into the wound site. Nanotechnology-based scaffolds are emphasized here. The discussion will be focused on the definition of critical quality attributes (chemical and physical characterization, stability, particle size, surface properties, release of nanoparticles from MDs, sterility and apyrogenicity), the preclinical evaluation (biocompatibility testing, alternative
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.