Evidence map›Paper›PMID 32867207›Full record

ArticleToxins2020

Fraternine, a Novel Wasp Peptide, Protects against Motor Impairments in 6-OHDA Model of Parkinsonism.

Andréia Mayer Biolchi, Danilo Gustavo Rodrigues de Oliveira, Henrique de Oliveira Amaral, Gabriel Avohay Alves Campos, Jacqueline Coimbra Gonçalves, Adolfo Carlos Barros de Souza, Marcos Robalinho Lima, Luciano Paulino Silva, Márcia Renata Mortari

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxins, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Andréia Mayer BiolchiLaboratory of Neuropharmacology, Department of Physiological Sciences, University of Brasília, Brasília, DF 70910-900, Brazil.
Danilo Gustavo Rodrigues de OliveiraLaboratory of Neuropharmacology, Department of Physiological Sciences, University of Brasília, Brasília, DF 70910-900, Brazil.
Henrique de Oliveira AmaralLaboratory of Neuropharmacology, Department of Physiological Sciences, University of Brasília, Brasília, DF 70910-900, Brazil.
Gabriel Avohay Alves CamposLaboratory of Neuropharmacology, Department of Physiological Sciences, University of Brasília, Brasília, DF 70910-900, Brazil.
Jacqueline Coimbra GonçalvesLaboratory of Neuropharmacology, Department of Physiological Sciences, University of Brasília, Brasília, DF 70910-900, Brazil.
Adolfo Carlos Barros de SouzaLaboratory of Neuropharmacology, Department of Physiological Sciences, University of Brasília, Brasília, DF 70910-900, Brazil.
Marcos Robalinho LimaLaboratory of Neuropharmacology, Department of Physiological Sciences, University of Brasília, Brasília, DF 70910-900, Brazil.ORCID 0000-0002-5901-0911
Luciano Paulino SilvaLaboratory of Mass Spectrometry, Embrapa Genetic Resources and Biotechnology, Brasília, DF 70770917, Brazil.ORCID 0000-0001-9075-7725
Márcia Renata MortariLaboratory of Neuropharmacology, Department of Physiological Sciences, University of Brasília, Brasília, DF 70910-900, Brazil.
Universidade de Brasília · BRBrazilian Agricultural Research Corporation · BRUniversidade Estadual de Londrina · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 470532/2011-4
6 · The paper itself

Abstract

Parkinson's disease (PD) is a progressive neurodegenerative condition that affects the Central Nervous System (CNS). Insect venoms show high molecular variability and selectivity in the CNS of mammals and present potential for the development of new drugs for the treatment of PD. In this study, we isolated and identified a component of the venom of the social wasp

Indexed as

AnimalsBehavior, AnimalCell DeathDisease Models, AnimalDopaminergic NeuronsFemaleMaleMiceMotor ActivityNerve DegenerationNeuroprotective AgentsOxidopamineParkinsonian DisordersPeptidesRotarod Performance TestSubstantia NigraNeuroprotective AgentsOxidopaminePeptidesWasp Venomsantiparkinsonian activitymotor behaviorneuroprotective effectParkinson’s diseasewasp venom

Identifiers

PMID32867207
PMCPMC7551070
OpenAlexW3081674900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.