Evidence map›Paper›PMID 32867122›Full record

ReviewAntibiotics (Basel, Switzerland)2020

Systematic Review on the Impact of Guidelines Adherence on Antibiotic Prescription in Respiratory Infections.

Inês Oliveira, Catarina Rego, Guilherme Semedo, Daniel Gomes, Adolfo Figueiras, Fátima Roque, Maria Teresa Herdeiro

Abstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
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  5. Review
  6. The impact of an institutional sepsis guideline on selecting appropriate empirical treatment in patients with carbapenem-resistant gram-negative bacilli bacteremia.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Inês OliveiraFaculty of Health, Medicine and Life Sciences, University of Maastricht, 6200 MD Maastricht, The Netherlands.
Catarina RegoFaculty of Pharmacy of the University of Lisbon, 1649 Lisbon, Portugal.
Guilherme SemedoDepartment of Medical Sciences, University of Aveiro, 3810 Aveiro, Portugal.
Daniel GomesResearch Unit for Inland Development, Polytechnic of Guarda (UDI-IPG), 6300 Guarda, Portugal.ORCID 0000-0003-2877-609X
Adolfo FigueirasDepartment of Preventive Medicine and Public Health, University of Santiago de Compostela, 15702 Santiago de Compostela, Spain.
Fátima RoqueResearch Unit for Inland Development, Polytechnic of Guarda (UDI-IPG), 6300 Guarda, Portugal.ORCID 0000-0003-0169-3788
Maria Teresa HerdeiroDepartment of Medical Sciences, Institute of Biomedicine-iBiMED, University of Aveiro, 3810 Aveiro, Portugal.ORCID 0000-0002-0500-4049

Funding

Fundação para a Ciência e a Tecnologia PTDC/SAU-SER/31678/2017
6 · The paper itself

Abstract

Overuse and inappropriate antibiotic prescription for respiratory tract infections (RTI) are one of the major contributors to the current antibiotic resistance problem. Guidelines provide support to prescribers for proper decision-making. Our purpose is to review the impact of prescribers' exposure to guidelines in antibiotic prescription for RTIs. A systematic review was performed searching in the scientific databases MEDLINE PubMed and EMBASE for studies which exposed prescribers to guidelines for RTI and compared antibiotic prescription rates/quality before and after the implementation, with thirty-four articles included in the review. The selected studies consisted on a simple intervention in the form of guideline implementation while others involved multifaceted interventions, and varied in population, designs, and settings. Prescription rate was shown to be reduced in the majority of the studies, along with an improvement in appropriateness, defined mainly by the prescription of narrow-spectrum rather than broad-spectrum antibiotics. Intending to ascertain if this implementation could decrease prescription costs, 7 articles accessed it, of which 6 showed the intended reduction. Overall interventions to improve guidelines adherence can be effective in reducing antibiotic prescriptions and inappropriate antibiotic selection for RTIs, supporting the importance of implementing guidelines in order to decrease the high levels of antibiotic prescriptions, and consequently reduce antimicrobial resistance.

Indexed as

adherenceantibiotic prescriptionguidelinesrespiratory tract infectionsreview

Identifiers

PMID32867122
PMCPMC7557871

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.