ArticleFoods (Basel, Switzerland)2020
Identification and Antimicrobial Activity of Medium-Sized and Short Peptides from Yellowfin Tuna (
Article in Foods (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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Who cites it
10 citing papers in PubMed, 37 citations in OpenAlex.
- Article
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- Targeted metabolomics of muscle amino acid profles and hepatic transcriptomics analyses in grass carp (Heliyon · 2024Article
- Apple Blossom Agricultural Residues as a Sustainable Source of Bioactive Peptides through Microbial Fermentation Bioprocessing.Antioxidants (Basel, Switzerland) · 2024Article
- Novel Insights for Metabiotics Production by Using Artisanal Probiotic Cultures.Microorganisms · 2021Review
- Lactoferrin, Quercetin, and Hydroxyapatite Act Synergistically againstInternational journal of molecular sciences · 2021Article
- Physicochemical and Functional Properties of Snack Bars Enriched with Tilapia (Foods (Basel, Switzerland) · 2021Article
- Muscle Protein Hydrolysates and Amino Acid Composition in Fish.Marine drugs · 2021Review
- Proteins and Bioactive Peptides in High Protein Content Foods.Foods (Basel, Switzerland) · 2021Article
- Production and Characterization of Medium-Sized and Short Antioxidant Peptides from Soy Flour-Simulated Gastrointestinal Hydrolysate.Antioxidants (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Due to the rapidly increasing resistance to conventional antibiotics, antimicrobial peptides are emerging as promising novel drug candidates. In this study, peptide fragments were obtained from yellowfin tuna muscle by simulated gastrointestinal digestion, and their antimicrobial activity towards Gram-positive and Gram-negative bacteria was investigated. In particular, the antimicrobial activity of both medium- and short-sized peptides was investigated by using two dedicated approaches. Medium-sized peptides were purified by solid phase extraction on C18, while short peptides were purified thanks to a graphitized carbon black sorbent. For medium-sized peptide characterization, a peptidomic strategy based on shotgun proteomics analysis was employed, and identification was achieved by matching protein sequence database by homology, as yellowfin tuna is a non-model organism, leading to the identification of 403 peptides. As for short peptide sequences, an untargeted suspect screening approach was carried out by means of an inclusion list presenting the exact mass to charge ratios (
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Registered trials
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