ArticlePolymers2020
pH-Responsive Gamma-Irradiated Poly(Acrylic Acid)-Cellulose-Nanocrystal-Reinforced Hydrogels.
Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Who cites it
9 citing papers in PubMed, 46 citations in OpenAlex.
- Drug-Loaded Hydrogel Microneedles for Sustainable Transdermal Delivery of Macromolecular Proteins.Current drug delivery · 2026Article
- Obtaining and Characterizing Poly(Acid Acrylic-co-Acrylamide) Hydrogels Reinforced with Cellulose Nanocrystals fromGels (Basel, Switzerland) · 2025Article
- Cutting-Edge Hydrogel Technologies in Tissue Engineering and Biosensing: An Updated Review.Materials (Basel, Switzerland) · 2024Review
- Inhibition of Adherence and Biofilm Formation ofMicroorganisms · 2023Article
- Mesoporous Materials Make Hydrogels More Powerful in Biomedicine.Gels (Basel, Switzerland) · 2023Review
- Swelling and Viscoelastic Properties of Cellulose-Based Hydrogels Prepared by Free Radical Polymerization of Dimethylaminoethyl Methacrylate in Cellulose Solution.Gels (Basel, Switzerland) · 2023Article
- Polymeric Biomaterials for Topical Drug Delivery in the Oral Cavity: Advances on Devices and Manufacturing Technologies.Pharmaceutics · 2022Review
- Recent Progress of Cellulose-Based Hydrogel Photocatalysts and Their Applications.Gels (Basel, Switzerland) · 2022Review
- Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
A pH-sensitive poly(acrylic acid) composite hydrogel was successfully synthesized via gamma irradiation and reinforced with cellulosic materials of different sizes. Cellulose was extracted from rice husks via alkali and bleaching treatment, and an acid hydrolysis treatment was performed to extract cellulose nanocrystals (CNCs). Morphological observation of cellulose and CNCs using scanning electron microscopy (SEM) and transmission electron microscopy (TEM) revealed diameters of 22-123 μm and 5-16 nm, respectively. The swelling properties of the fabricated poly(acrylic acid)/cellulosic hydrogels were found to respond to changes in pH, and CNC-reinforced hydrogels performed better than cellulose-reinforced hydrogels. The highly crystalline CNC provided a greater storage modulus, hence acting as a better reinforcing material for poly(acrylic acid)-based hydrogels. SEM showed that hydrogels reinforced with the CNC nanofillers contained a homogeneous pore distribution and produced better interfacial interactions than those reinforced with the cellulose microfillers, thus performing better as hydrogels. These findings demonstrate that gamma-irradiated poly(acrylic acid) hydrogels reinforced with CNCs exhibit a better stimuli response toward pH than poly(acrylic acid) hydrogels reinforced with cellulose.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.