ArticleNature2020
Human germinal centres engage memory and naive B cells after influenza vaccination.
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Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 219 papers.
0numbers the graph read from it
0cells of the map it votes in
219citing papers in PubMed
27.5field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
219 citing papers in PubMed, 299 citations in OpenAlex.
- Vaccination induces HIV broadly neutralizing antibody precursors in humans.Science (New York, N.Y.) · 2022Trial
- A n-heneicosane solid emulsion as a single-dose subunit vaccine elicits broad and durable immune responses in an aged and a Pox virus model.International journal of pharmaceutics: X · 2026Article
- Expression patterns of CD24 and CD27 resolve the origins and gradual differentiation of CD11cThe EMBO journal · 2026Article
- Targeting T follicular helper cells for lifelong health.Nature reviews. Drug discovery · 2026Review
- High Frequency of Circulating IL-4RJournal of clinical and translational hepatology · 2026Article
- Near real-time data on the human neutralizing antibody landscape to influenza virus in summer of 2026 shows antigenic advance of H3N2 subclade K region D mutants and H1N1 D.3.1.1 Sa mutants.bioRxiv : the preprint server for biology · 2026Article
- What Antibody Repertoires See: Structural and Immunogenetic Insights Into Influenza A Virus Hemagglutinin Recognition.Immunological reviews · 2026Review
- Pre-existing hemagglutinin-specific antibody levels are associated with B-cell repertoire maturation and antibody breadth after influenza vaccination.Virologica Sinica · 2026Article
- Article
- mRNA-based influenza vaccine expands the B cell response breadth in humans.Nature immunology · 2026Observational
- Lymphoid-Tissue-on-Chip Recapitulates Human Antibody Responses In Vitro.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Human Organoids as a Novel Tool for Vaccine Study.Advanced healthcare materials · 2026Review
- Clonal dynamics of germinal center refueling by secondary immunization.bioRxiv : the preprint server for biology · 2026Article
- Affinity-matured B cell responses neutralizing type-I interferons underlie severe viral infections.Cell · 2026Article
- Article
- Local B cell immunity and durable memory after live-attenuated influenza intranasal vaccination of humans.Science translational medicine · 2026Article
- Immunological memory to vaccines.Immunity · 2026Review
- IFN-gene signatures in B cells following influenza A and B virus infection and influenza vaccination.EMBO molecular medicine · 2026Article
- A Human Lymph node-on-a-Chip for Personalized Evaluation of Vaccine Immunogenicity.Research square · 2026Article
- Near real-time data on the human neutralizing antibody landscape to influenza virus as of early 2026 to inform vaccine-strain selection.bioRxiv : the preprint server for biology · 2026Article
159 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
23 authors at 4 institutions in 1 country.
Jackson S Turner *Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.ORCID http://orcid.org/0000-0002-4396-6265
Julian Q Zhou *Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0001-9602-2092
Julianna Han *Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.
Aaron J SchmitzDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.ORCID http://orcid.org/0000-0002-8077-6751
Amena A RizkDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Wafaa B AlsoussiDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Tingting LeiDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Mostafa AmorDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Katherine M McIntireDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Philip MeadeDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Shirin StrohmeierDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Rafael I BrentDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.ORCID http://orcid.org/0000-0002-3233-7914
Sara T RicheyDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.
Alem HaileClinical Trials Unit, Washington University School of Medicine, St Louis, MO, USA.
Yuhe R YangDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.
Michael K KlebertClinical Trials Unit, Washington University School of Medicine, St Louis, MO, USA.
Teresa SuessenDepartment of Radiology, Washington University School of Medicine, St Louis, MO, USA.
Sharlene TeefeyDepartment of Radiology, Washington University School of Medicine, St Louis, MO, USA.
Rachel M PrestiDepartment of Internal Medicine-Infectious Diseases, Washington University School of Medicine, St Louis, MO, USA.
Florian KrammerDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0003-4121-776X
Steven H KleinsteinInterdepartmental Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0003-4957-1544
Andrew B WardDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-7153-3769
Ali H EllebedyDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA. ellebedy@wustl.edu.
Washington University in St. Louis · USScripps Research Institute · USIcahn School of Medicine at Mount Sinai · USYale University · US
Funding
Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M COLLABORATIVE INFLUENZA VACCINE INNOVATION CENTER: UNIVERSAL INFLUENZA VACCINE RESEARCH75N93019C00051 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KRAMMER, FLORIAN · 2019 to 2025
$105.4MWU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8MSystems investigation of vaccine responses in B cell depleted autoimmune patientsU19AI089992 · NIAID · YALE UNIVERSITY · PI David A. Hafler, RUTH R MONTGOMERY · 2010 to 2026
$50.4MWashington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4MTRAINING IN THE IMMUNOBIOLOGY AND MOLECULAR CELL BIOLOGY OF CANCERT32CA009547 · NCI · WASHINGTON UNIVERSITY · PI ROBERT DAVID SCHREIBER · 1986 to 2026
$12.1MPATHOGENESIS AND IMMUNOLOGY OF DISEASET32AI007244 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI NEMAZEE, DAVID · 1985 to 2022
$8.8MProgramming Durable Immune Responses To VaccinationU01AI141990 · NIAID · WASHINGTON UNIVERSITY · PI Ali Hassan Ellebedy · 2019 to 2026
$5.3MCOMPUTATIONAL TOOLS FOR THE ANALYSIS OF HIGH-THROUGHPUT IMMUNOGLOBULIN SEQUENCING EXPERIMENTSR01AI104739 · NIAID · YALE UNIVERSITY · PI KLEINSTEIN, STEVEN H. · 2014 to 2022
$3.6MBroad humoral protection induced by influenza B neuraminidase-based immunogensR01AI117287 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KRAMMER, FLORIAN · 2016 to 2020
$2.4MCONTROL OF ADAPTIVE IMMUNITY BY ACTIN-REGULATORY PROTEINSR01AI104732 · NIAID · WASHINGTON UNIVERSITY · PI MORLEY, SHARON CELESTE · 2014 to 2018
$1.9MAntibody responses in humans after infection with avian influenza virusesR01AI128821 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KRAMMER, FLORIAN · 2017 to 2021
$1.0MNCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NCI NIH HHS P30 CA091842NCI NIH HHS T32 CA009547NIAID NIH HHS 2 T32 AI007244-36NIAID NIH HHS 5T32CA009547NIAID NIH HHS 75N93019C00051NIAID NIH HHS AI117287NIAID NIH HHS AI128821NIAID NIH HHS HHSN272201400006CNIAID NIH HHS HHSN272201400008CNIAID NIH HHS R01 AI104732NIAID NIH HHS R01 AI104739NIAID NIH HHS R01 AI117287NIAID NIH HHS R01 AI128821NIAID NIH HHS R21 AI139813NIAID NIH HHS R56 AI117287NIAID NIH HHS T32 AI007244NIAID NIH HHS U01 AI141990NIAID NIH HHS U19 AI089992
Abstract
Influenza viruses remain a major public health threat. Seasonal influenza vaccination in humans primarily stimulates pre-existing memory B cells, which differentiate into a transient wave of circulating antibody-secreting plasmablasts
Indexed as
AdultAnimalsB-LymphocytesClone CellsEpitope MappingFemaleGerminal CenterHumansImmunologic MemoryInfluenza, HumanInfluenza VaccinesMaleMiceInfluenza Vaccines
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.