Evidence map›Paper›PMID 32866858›Full record

Observational studyEuropean journal of obstetrics, gynecology, and reproductive biology2020

Influence of COVID-19 pandemic on the psychological status of infertile couples.

Veronica Esposito, Erika Rania, Daniela Lico, Sara Pedri, Alessia Fiorenza, Marina Francesca Strati, Alessandro Conforti, Vinenzo Marrone, Andrea Carosso, Alberto Revelli and 3 more

Registry-linked trialOpen access · bronzeAbstract readObservational Study
In one paragraph

Observational study in European journal of obstetrics, gynecology, and reproductive biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05063942 (Does Covid-19 Vaccination in Patients Undergoing in Vitro Fertilization Affect the Live Birth Rate of Their First Embryo Transfer Cycle), which is not on this map. Cited by 38 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 3 pooled it
12.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05063942 unknown statusnot on this mapstarted 2021, after this paper: background citation

Does Covid-19 Vaccination in Patients Undergoing in Vitro Fertilization Affect the Live Birth Rate of Their First Embryo Transfer Cycle: A Prospective Cohort Study

TypeobservationalSponsorShanghai First Maternity and Infant HospitalRan2021 to 2023Enrolled712ConditionsCovid-19 Vaccination
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 3 syntheses or guidelines pooled it, 86 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Worldwide beliefs among pregnant women on SARS-CoV-2 vaccine: a systematic review.European journal of obstetrics, gynecology, and reproductive biology · 2022
    Pooled it
  4. Article
  5. Observational
  6. Review
  7. Article
  8. Article
  9. Article
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  12. SARS-CoV-2, fertility and assisted reproduction.Human reproduction update · 2023
    Review
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  14. Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Veronica EspositoDepartment of Experimental and Clinical Medicine, Chair of Obstetrics and Gynecology, Magna Graecia University of Catanzaro, ART Public Centre, Pugliese Ciaccio Hospital, viale Pio X, 88100 Catanzaro, Italy.
Erika RaniaDepartment of Experimental and Clinical Medicine, Chair of Obstetrics and Gynecology, Magna Graecia University of Catanzaro, ART Public Centre, Pugliese Ciaccio Hospital, viale Pio X, 88100 Catanzaro, Italy. Electronic address: rania.erika@gmail.com.
Daniela LicoDepartment of Experimental and Clinical Medicine, Chair of Obstetrics and Gynecology, Magna Graecia University of Catanzaro, ART Public Centre, Pugliese Ciaccio Hospital, viale Pio X, 88100 Catanzaro, Italy.
Sara PedriDepartment of Experimental and Clinical Medicine, Chair of Obstetrics and Gynecology, Magna Graecia University of Catanzaro, ART Public Centre, Pugliese Ciaccio Hospital, viale Pio X, 88100 Catanzaro, Italy.
Alessia FiorenzaDepartment of Experimental and Clinical Medicine, Chair of Obstetrics and Gynecology, Magna Graecia University of Catanzaro, ART Public Centre, Pugliese Ciaccio Hospital, viale Pio X, 88100 Catanzaro, Italy.
Marina Francesca StratiDepartment of Experimental and Clinical Medicine, Chair of Obstetrics and Gynecology, Magna Graecia University of Catanzaro, ART Public Centre, Pugliese Ciaccio Hospital, viale Pio X, 88100 Catanzaro, Italy.
Alessandro ConfortiDepartment of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples, Federico II Via Pansini 5, 80131 Naples, Italy.
Vinenzo MarroneDepartment of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples, Federico II Via Pansini 5, 80131 Naples, Italy.
Andrea CarossoGynecology and Obstetrics 1, Physiopathology of Reproduction and IVF Unit, Department of Surgical Sciences, S. Anna Hospital, University of Torino, Via Ventimiglia 3, 10126, Turin, Italy.
Alberto RevelliGynecology and Obstetrics 1, Physiopathology of Reproduction and IVF Unit, Department of Surgical Sciences, S. Anna Hospital, University of Torino, Via Ventimiglia 3, 10126, Turin, Italy.
Fulvio ZulloDepartment of Experimental and Clinical Medicine, Chair of Obstetrics and Gynecology, Magna Graecia University of Catanzaro, ART Public Centre, Pugliese Ciaccio Hospital, viale Pio X, 88100 Catanzaro, Italy; Department of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples, Federico II Via Pansini 5, 80131 Naples, Italy.
Costantino Di CarloDepartment of Experimental and Clinical Medicine, Chair of Obstetrics and Gynecology, Magna Graecia University of Catanzaro, ART Public Centre, Pugliese Ciaccio Hospital, viale Pio X, 88100 Catanzaro, Italy.
Roberta VenturellaDepartment of Experimental and Clinical Medicine, Chair of Obstetrics and Gynecology, Magna Graecia University of Catanzaro, ART Public Centre, Pugliese Ciaccio Hospital, viale Pio X, 88100 Catanzaro, Italy.
Magna Graecia University · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

OBJECTIVE(S): to evaluate the impact of the COVID-19 pandemic on infertile couples' emotions, anxiety and future plans. STUDY

designAn observational study was perfomed by Italian ART centers and online forums. In this study, infertile couples candidate to ART and whose treatment was blocked due to the COVID-19 lockdown were enrolled through an online survey. The psychological impact of COVID-19 was measured by Impact of Event Scale-Revised (IES-R) and by a short form of the Spielberger State-Trait Anxiety Inventory (STAI); Self-perceived anxiety related either to pregnancy safety and to economic crisis measured by VAS scale.

results627 patients completed the survey. The COVID-19 lock-down had a moderate/severe psychological impact on infertile patients (mean IES-R score 36.4 ± 16.6). The mean STAI score was 49.8 ± 15.3, with an overall incidence of STAI > 36 of 71 %. The mean VAS scale for anxiety perception was 45.3 ± 15.3. Women were more emotionally distressed, anxious and depressed than men (36.8 ± 16.4 vs 31.0 ± 18.4 for IES-R, respectively; p = 0.03). Notwithstanding the uncertainty about pregnancy safety, 64.6 % of respondents chose to maintain their reproductive programme. Economic crisis induced 11.5 % of the surveyed patients to give up their ART program. Respondents who had at least one relative affected by COVID-19 had a significantly higher IES-R score and anxiety VAS, but not higher STAI scores, than patients belonging to unaffected families. CONCLUSION(S): COVID-19 pandemic itself and the recommendation to stop ART program generated higher distress levels in infertile couples. The psychological impact of COVID-19 pandemic in infertility patients should not be underestimated, and a specific psychological support should be planned.

Indexed as

AdultAnxietyBetacoronavirusCoronavirus InfectionsCOVID-19EmotionsFemaleHealth StatusHumansInfertilityItalyMalePandemicsPneumonia, ViralPregnancyPregnancy Complications, InfectiousAnxietyCOVID-19DistressInfertilityPandemicPsychological impact

Identifiers

PMID32866858
PMCPMC7443353
OpenAlexW3081418839

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.