ArticleVirus research2020
Association of vitamin D with the modulation of the disease severity in COVID-19.
Article in Virus research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 10 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 10 syntheses or guidelines pooled it, 66 citations in OpenAlex.
- Association of vitamin D deficiency with COVID-19 infection severity: Systematic review and meta-analysis.Clinical endocrinology · 2022Pooled it
- Insufficient evidence for vitamin D use in COVID-19: A rapid systematic review.International journal of clinical practice · 2021Pooled it
- Association of Vitamin D Status with SARS-CoV-2 Infection or COVID-19 Severity: A Systematic Review and Meta-analysis.Advances in nutrition (Bethesda, Md.) · 2021Pooled it
- The link between COVID-19 and VItamin D (VIVID): A systematic review and meta-analysis.Metabolism: clinical and experimental · 2021Pooled it
- Micronutrients Deficiency, Supplementation and Novel Coronavirus Infections-A Systematic Review and Meta-Analysis.Nutrients · 2021Pooled it
- Low vitamin D status is associated with coronavirus disease 2019 outcomes: a systematic review and meta-analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021Pooled it
- A systematic review and meta-analysis of effect of vitamin D levels on the incidence of COVID-19.Cardiology journal · 2021Pooled it
- Vitamin D Status and SARS-CoV-2 Infection and COVID-19 Clinical Outcomes.Frontiers in public health · 2021Pooled it
- Plant-Derived Food Grade Substances (PDFGS) Active Against Respiratory Viruses: A Systematic Review of Non-clinical Studies.Frontiers in nutrition · 2021Pooled it
- The role of vitamin D deficiency on COVID-19: a systematic review and meta-analysis of observational studies.Epidemiology and health · 2021Pooled it
- Dietary patterns and micronutrients in respiratory infections including COVID-19: a narrative review.BMC public health · 2024Review
- Vitamin D Levels in COVID-19 and NonCOVID-19 Pediatric Patients and Its Relationship with Clinical and Laboratory Characteristics.Biomedicines · 2024Article
- Potential Laboratory Markers in COVID-19 Patients with Gastrointestinal Impairments as Prognosticators of the Disease Severity.Tanaffos · 2024Article
- The Impact of Serum Levels of Reactive Oxygen and Nitrogen Species on the Disease Severity of COVID-19.International journal of molecular sciences · 2023Article
- The Effect of Vitamin D Adequacy on Thyroid Hormones and Inflammatory Markers after Bariatric Surgery.Metabolites · 2023Article
- Vitamin D-A prominent immunomodulator to prevent COVID-19 infection.International journal of rheumatic diseases · 2023Review
- The Impact of Serum Levels of Vitamin D3 and Its Metabolites on the Prognosis and Disease Severity of COVID-19.Nutrients · 2022Article
- Article
- A multi-objective location-routing model for dental waste considering environmental factors.Annals of operations research · 2022Article
- COVID-19 and Vitamin D- a Systematic Review.Zdravstveno varstvo · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In late 2019, SARS-CoV-2 started to spread throughout the world causing the COVID-19 that has taken a considerable number of lives. Results obtained from several investigations have explained the virus origin, pathogenicity, and transmission. Similar to SARS coronavirus, the pulmonary angiotensin converting enzyme (ACE) 2 was introduced as the virus receptor for entering the cell. An increased body of epidemiological and clinical evidences has shown modulating effects of vitamin D in lung injuries through several mechanisms. Several clinical symptoms as well as molecular factors have shown to be related to the disease transmission and severity. In this study, vitamin D, ACE concentrations, and neutrophil to lymphocyte ratio (NLR) were measured in patients with confirmed COVID-19 in comparison with control group. Results demonstrated significant alterations in vitamin D and ACE levels as well as NLR in the patients' group. Contribution of those factors with the prognosis and severity of the disease has been shown.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.