Evidence map›Paper›PMID 32866426›Full record

ArticleAutophagy2021

Keratinocyte autophagy enables the activation of keratinocytes and fibroblastsand facilitates wound healing.

Lei Qiang, Seungwon Yang, Yan-Hong Cui, Yu-Ying He

Open access · bronzeAbstract read
In one paragraph

Article in Autophagy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers.

0numbers the graph read from it
0cells of the map it votes in
118citing papers in PubMed
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

118 citing papers in PubMed, 221 citations in OpenAlex.

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  7. Determining the concentration of golden sea cucumber (Journal of Taibah University Medical Sciences · 2026
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  15. Science advances · 2026
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58 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Lei QiangDepartment of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA.
Seungwon YangDepartment of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA.
Yan-Hong CuiDepartment of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA.
Yu-Ying HeDepartment of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA.ORCID 0000-0002-2665-7962
University of Chicago · USChina Pharmaceutical University · CN

Funding

VIRAL ONCOLOGY CORE FACILITYP30CA014599 · NCI · UNIVERSITY OF CHICAGO · PI MARK W. LINGEN · 1985 to 2026
$122.1M
Re-Engineering Translational Research at the University of ChicagoUL1TR000430 · NCATS · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2012 to 2016
$20.2M
Pilot Program CoreP30ES027792 · NIEHS · UNIVERSITY OF CHICAGO · PI Gokhan M. Mutlu, Gail S Prins · 2017 to 2026
$13.6M
YTHDF2 and UVB damage response in skin cancerR01ES024373 · NIEHS · UNIVERSITY OF CHICAGO · PI HE, YU-YING · 2015 to 2023
$4.3M
The mechanistic role of METTL14 in UVB-induced skin tumorigenesisR01ES030576 · NIEHS · UNIVERSITY OF CHICAGO · PI HE, YU-YING · 2019 to 2023
$3.0M
FTO and RNA methylation in arsenic tumorigenicityR01ES031534 · NIEHS · UNIVERSITY OF CHICAGO · PI HE, YU-YING · 2020 to 2022
$1.2M
NCATS NIH HHS UL1 TR000430NCI NIH HHS P30 CA014599NIEHS NIH HHS P30 ES027792NIEHS NIH HHS R01 ES024373NIEHS NIH HHS R01 ES030576NIEHS NIH HHS R01 ES031534
6 · The paper itself

Abstract

Macroautophagy/autophagy is a cellular catabolic process that is implicated in several physiological and pathological processes. However, the role of epidermal autophagy in wound healing remains unknown. Here, using mice with genetic ablation of the essential

Indexed as

AutophagyKeratinocytesAnimalsAutophagy-Related Protein 5Beclin-1MiceWound HealingAutophagy-Related Protein 5Beclin-1AutophagyCCL2/MCP-1differentiationfibroblastinflammationkeratinocytemigrationproliferationTNFwound healing

Identifiers

PMID32866426
PMCPMC8496719
OpenAlexW3081733528

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.