Evidence map›Paper›PMID 32866086›Full record

ArticlePhysiological genomics2020

Methods and sensors for functional genomic studies of cell-cycle transitions in single cells.

Alexander C Zambon, Tom Hsu, Seunghee Erin Kim, Miranda Klinck, Jennifer Stowe, Lindsay M Henderson, Donald Singer, Leomar Patam, Curtis Lim, Andrew D McCulloch and 2 more

Abstract read
In one paragraph

Article in Physiological genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Monitoring the Cell Cycle of Tumor Cells in Mouse Models of Human Cancer.Cold Spring Harbor perspectives in medicine · 2023
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alexander C ZambonDepartment of Biopharmaceutical Sciences, School of Pharmacy and Health Sciences, Keck Graduate Institute, Claremont, California.ORCID 0000-0001-7874-4462
Tom HsuDepartment of Biopharmaceutical Sciences, School of Pharmacy and Health Sciences, Keck Graduate Institute, Claremont, California.
Seunghee Erin KimDepartment of Biopharmaceutical Sciences, School of Pharmacy and Health Sciences, Keck Graduate Institute, Claremont, California.
Miranda KlinckKeck Science Department, Pitzer College, Claremont, California.
Jennifer StoweDepartment of Bioengineering, University of California San Diego, La Jolla, California.
Lindsay M HendersonDepartment of Pharmacology, University of California San Diego, La Jolla, California.
Donald SingerStem Cells & Regenerative Medicine Laboratory, Peninsula Dental School, University of Plymouth, Plymouth, United Kingdom.
Leomar PatamDepartment of Biopharmaceutical Sciences, School of Pharmacy and Health Sciences, Keck Graduate Institute, Claremont, California.
Curtis LimDepartment of Pharmacology, University of California San Diego, La Jolla, California.
Andrew D McCullochDepartment of Bioengineering, University of California San Diego, La Jolla, California.
Bing HuStem Cells & Regenerative Medicine Laboratory, Peninsula Dental School, University of Plymouth, Plymouth, United Kingdom.
Anna I HickersonHenry E. Riggs School of Applied Life Sciences, Keck Graduate Institute, Claremont, California.

Funding

Systems Biology of Hypertrophic Heart Disease from Molecular Pathways to Organ SystemR01HL137100 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MCCULLOCH, ANDREW D. · 2017 to 2020
$2.0M
American Heart Association-American Stroke Association 10SDG2630130Biotechnology and Biological Sciences Research Council BB/L02392X/1Marie Curie FP7-PEOPLE-2013-CIGNHLBI NIH HHS R01 HL137100
6 · The paper itself

Abstract

Much of our understanding of the regulatory mechanisms governing the cell cycle in mammals has relied heavily on methods that measure the aggregate state of a population of cells. While instrumental in shaping our current understanding of cell proliferation, these approaches mask the genetic signatures of rare subpopulations such as quiescent (G

Indexed as

Genes, ReporterAnimalsCell CycleCell ProliferationEpithelial CellsFluorescent DyesGenetic VectorsGreen Fluorescent ProteinsHumansKi-67 AntigenMCF-7 CellsMiceMicroinjectionsPhenotypePlasmidsRNA, Messengerenhanced green fluorescent proteinFluorescent DyesGreen Fluorescent ProteinsKi-67 AntigenMKI67 protein, humanRNA, Messengercell cyclemicromanipulationquantitative-imagingquiescencesingle cell

Identifiers

PMID32866086
PMCPMC8828270

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.