Evidence map›Paper›PMID 32866011›Full record

ArticleJournal of the American Chemical Society2020

Synthesis of 9-Dechlorochrysophaentin A Enables Studies Revealing Bacterial Cell Wall Biosynthesis Inhibition Phenotype in

Christopher R Fullenkamp, Yen-Pang Hsu, Ellen M Quardokus, Gengxiang Zhao, Carole A Bewley, Michael VanNieuwenhze, Gary A Sulikowski

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. β-Lactams from the Ocean.Marine drugs · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christopher R FullenkampDepartment of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.
Yen-Pang HsuDepartment of Chemistry, Indiana University, Bloomington, Indiana 47405, United States.
Ellen M QuardokusDepartment of Chemistry, Indiana University, Bloomington, Indiana 47405, United States.
Gengxiang ZhaoLaboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States.
Carole A BewleyLaboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States.ORCID 0000-0003-2203-0852
Michael VanNieuwenhzeDepartment of Chemistry, Indiana University, Bloomington, Indiana 47405, United States.ORCID 0000-0001-6093-5949
Gary A SulikowskiDepartment of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.ORCID 0000-0002-1067-0767

Funding

Discovery, Structural Studies and Biosynthesis of Biologically Active Natural Products and Natural Product-Like InhibitorsZIADK031135 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI BEWLEY, CAROLE · 2009 to 2025
$16.9M
Chemistry-Biology Interface Training GrantT32GM065086 · NIGMS · VANDERBILT UNIVERSITY · PI BACHMANN, BRIAN O, SULIKOWSKI, GARY ALLEN · 2002 to 2022
$7.0M
Dynamics of bacterial peptidoglycan synthesisR01GM113172 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI BRUN, YVES V, VANNIEUWENHZE, MICHAEL S · 2015 to 2018
$3.5M
Supplement to Chemical Biology Studies of the Dynamics and Inhibition of Peptidoglycan BiosynthesisR35GM136365 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI VANNIEUWENHZE, MICHAEL S · 2020 to 2024
$2.0M
NIGMS NIH HHS R01 GM113172NIGMS NIH HHS R35 GM136365NIGMS NIH HHS T32 GM065086
6 · The paper itself

Abstract

Chrysophaentin A is an antimicrobial natural product isolated from the marine alga

Indexed as

Anti-Bacterial AgentsBacillus subtilisBiological ProductsCell WallEukaryotaMicrobial Sensitivity TestsMolecular StructurePhenotypeStereoisomerismAnti-Bacterial AgentsBiological Products

Identifiers

PMID32866011
PMCPMC7771388

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.