Evidence map›Paper›PMID 32865965›Full record

ArticleACS infectious diseases2020

Structural Basis for the Inhibitor and Substrate Specificity of the Unique Fph Serine Hydrolases of

Matthias Fellner, Christian S Lentz, Sam A Jamieson, Jodi L Brewster, Linhai Chen, Matthew Bogyo, Peter D Mace

Open access · greenAbstract read
In one paragraph

Article in ACS infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.3field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Unique structural and ligand-binding properties of theProceedings of the National Academy of Sciences of the United States of America · 2026
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  2. Unique structural and ligand binding properties of thebioRxiv : the preprint server for biology · 2025
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  6. DecipheringmSystems · 2024
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  11. Functional Annotation of Hypothetical Proteins From theBioinformatics and biology insights · 2022
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  12. Newly discoveredADMET & DMPK · 2022
    Review
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  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Matthias FellnerBiochemistry Department, School of Biomedical Sciences, University of Otago, Dunedin 9054, New Zealand.ORCID 0000-0003-3192-6984
Christian S LentzPathology, Microbiology and Immunology, Stanford University School of Medicine, Stanford, California 94305, United States.
Sam A JamiesonBiochemistry Department, School of Biomedical Sciences, University of Otago, Dunedin 9054, New Zealand.
Jodi L BrewsterBiochemistry Department, School of Biomedical Sciences, University of Otago, Dunedin 9054, New Zealand.
Linhai ChenPathology, Microbiology and Immunology, Stanford University School of Medicine, Stanford, California 94305, United States.
Matthew BogyoPathology, Microbiology and Immunology, Stanford University School of Medicine, Stanford, California 94305, United States.ORCID 0000-0003-3753-4412
Peter D MaceBiochemistry Department, School of Biomedical Sciences, University of Otago, Dunedin 9054, New Zealand.
University of Otago · NZShanghai Institute of Materia Medica · CNStanford University · USUiT The Arctic University of Norway · NO

Funding

Staphylococcus serine hydrolases as targets for therapeutic and imaging contrast agentsR01EB026332 · NIBIB · STANFORD UNIVERSITY · PI BOGYO, MATTHEW · 2018 to 2021
$1.4M
NIBIB NIH HHS R01 EB026332
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Staphylococcal InfectionsStaphylococcus aureusAnimalsHydrolasesSerineSubstrate SpecificityHydrolasesSerineactivity-based probeacylinhibitorserine hydrolasesStaphylococcus aureus

Identifiers

PMID32865965
PMCPMC12914646
OpenAlexW3081704927

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.