Evidence map›Paper›PMID 32865839›Full record

ReviewThe Prostate2020

Meeting report from the Prostate Cancer Foundation PSMA theranostics state of the science meeting.

Andrea K Miyahira, Kenneth J Pienta, John W Babich, Neil H Bander, Jeremie Calais, Peter Choyke, Michael S Hofman, Steven M Larson, Frank I Lin, Michael J Morris and 6 more

Open access · bronzeAbstract readReview
In one paragraph

Review in The Prostate, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Clinical research analysis of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Review
  3. Review
  4. Advances in PSMA-Targeted Radionuclide Therapeutics.Current treatment options in oncology · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Modular Smart Molecules for PSMA-Targeted Chemotherapy.Molecular cancer therapeutics · 2022
    Article
  10. Article
  11. An ImprovedJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  12. Review
  13. Review
  14. Article
  15. Preclinical Evaluation ofPharmaceutics · 2021
    Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 2 countries.

Andrea K MiyahiraScience Department, Prostate Cancer Foundation, Santa Monica, California.ORCID 0000-0003-4976-002X
Kenneth J PientaDepartment of Urology, The Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0002-4138-2186
John W BabichDepartment of Radiology, Weill Cornell Medicine, New York, New York.ORCID 0000-0002-1616-3416
Neil H BanderLaboratory of Urologic Oncology, Department of Urology and Meyer Cancer Center, Weill Cornell Medicine, New York, New York.ORCID 0000-0003-4642-0759
Jeremie CalaisAhmanson Translational Theranostics Division, Department of Molecular & Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.ORCID 0000-0002-8839-4379
Peter ChoykeMolecular Imaging Program, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Michael S HofmanProstate Cancer Theranostics and Imaging Centre of Excellence (ProsTIC), Peter MacCallum Cancer Centre, The University of Melbourne, Melbourne, Australia.ORCID 0000-0001-8622-159X
Steven M LarsonDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Frank I LinMolecular Imaging Program, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.ORCID 0000-0003-3539-1454
Michael J MorrisGenitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0002-9454-0096
Martin G PomperDepartment of Urology, The Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Shahneen SandhuProstate Cancer Theranostics and Imaging Centre of Excellence (ProsTIC), Peter MacCallum Cancer Centre, The University of Melbourne, Melbourne, Australia.ORCID 0000-0002-8660-4475
Howard I ScherGenitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0002-6791-9324
Scott T TagawaDivision of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medicine, New York, New York.ORCID 0000-0003-2777-8587
Scott WilliamsProstate Cancer Theranostics and Imaging Centre of Excellence (ProsTIC), Peter MacCallum Cancer Centre, The University of Melbourne, Melbourne, Australia.ORCID 0000-0002-1357-0884
Howard R SouleScience Department, Prostate Cancer Foundation, Santa Monica, California.
Cornell University · USMemorial Sloan Kettering Cancer Center · USThe University of Melbourne · AUJohns Hopkins University · USNational Cancer Institute · USProstate Cancer Foundation · USUniversity of California, Los Angeles · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
PSMA-based Cancer Imaging AgentsR01CA134675 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI POMPER, MARTIN G · 2009 to 2025
$6.2M
Small Molecule PSMA-Targeted Alpha TherapyR01CA184228 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI POMPER, MARTIN G, ZALUTSKY, MICHAEL ROD · 2014 to 2023
$3.6M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA134675NCI NIH HHS R01 CA184228
6 · The paper itself

Abstract

introductionThe Prostate Cancer Foundation (PCF) convened a PCF prostate-specific membrane antigen (PSMA) Theranostics State of the Science Meeting on 18 November 2019, at Weill Cornell Medicine, New York, NY.

methodsThe meeting was attended by 22 basic, translational, and clinical researchers from around the globe, with expertise in PSMA biology, development and use of PSMA theranostics agents, and clinical trials. The goal of this meeting was to discuss the current state of knowledge, the most important biological and clinical questions, and critical next steps for the clinical development of PSMA positron emission tomography (PET) imaging agents and PSMA-targeted radionuclide agents for patients with prostate cancer.

resultsSeveral major topic areas were discussed including the biology of PSMA, the role of PSMA-targeted PET imaging in prostate cancer, the physics and performance of different PSMA-targeted PET imaging agents, the current state of clinical development of PSMA-targeted radionuclide therapy (RNT) agents, the role of dosimetry in PSMA RNT treatment planning, barriers and challenges in PSMA RNT clinical development, optimization of patient selection for PSMA RNT trials, and promising combination treatment approaches with PSMA RNT. DISCUSSION: This article summarizes the presentations from the meeting for the purpose of globally disseminating this knowledge to advance the use of PSMA-targeted theranostic agents for imaging and treatment of patients with prostate cancer.

Indexed as

HumansMaleMolecular Targeted TherapyPrecision MedicineProstatic NeoplasmsTheranostic Nanomedicineclinical trialsmedical oncologynuclear medicinePET imagingprostate-specific membrane antigen (PSMA)radiation therapyradiologyradionuclidesradiopharmaceuticalsurology

Identifiers

PMID32865839
PMCPMC8442561
OpenAlexW3082227618

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.