ReviewClinical autonomic research : official journal of the Clinical Autonomic Research Society2020
Sex differences in vascular transduction of sympathetic nerve activity.
Review in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05997732 (Sympathetic Neurovascular Transduction), which is not on this map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Sympathetic Neurovascular Transduction: Role of Adrenergic Receptors and Sex Differences
Who cites it
20 citing papers in PubMed, 34 citations in OpenAlex.
- Resting sympathetic transduction in veterans with PTSD.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026Article
- The role of peripheral venous distension reflex in regulating hemodynamics: mini review.Autonomic neuroscience : basic & clinical · 2024Review
- Influence of sex and sedentary conditions on sympathetic burst characteristics in prepubertal, postpubertal, and young adult rats.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Higher sympathetic transduction is independently associated with greater very short-term diastolic blood pressure variability in young healthy males and females.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2023Article
- Diversity of cells and signals in the cardiovascular system.The Journal of physiology · 2023Article
- Sympathetic transduction to blood pressure during euglycemic-hyperinsulinemia in young healthy adults: role of burst amplitude.American journal of physiology. Regulatory, integrative and comparative physiology · 2023Article
- Comparison of signal-averaging and regression approaches to analyzing sympathetic transduction.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022Article
- Sympathetic-mediated blunting of forearm vasodilation is similar between young men and women.Biology of sex differences · 2022Article
- Impact of sampling duration on spontaneous sympathetic transduction.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022Article
- Heart Rate Recovery, Central Systolic Pressure, and Augmentation Index in Young Healthy Individuals.Vascular health and risk management · 2022Article
- Circadian and sex differences in carotid-femoral pulse wave velocity in young individuals and elderly with and without type 2 diabetes.Frontiers in cardiovascular medicine · 2022Article
- Advances in pathogenesis and treatment of essential hypertension.Frontiers in cardiovascular medicine · 2022Review
- Aerobic fitness is inversely associated with neurohemodynamic transduction and blood pressure variability in older adults.GeroScience · 2021Article
- Forearm vascular resistance responses to the Valsalva maneuver in healthy young and older adults.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2021Article
- Does COVID-19 influence the sympathetic regulation of blood pressure?The Journal of physiology · 2021Article
- Sex-dependent development of enhanced sympathoexcitation in sedentary versus physically active rats.The Journal of physiology · 2021Article
- The impact of ageing and sex on sympathetic neurocirculatory regulation.Seminars in cell & developmental biology · 2021Review
- Aerobic fitness and sympathetic responses to spontaneous muscle sympathetic nerve activity in young males.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2021Article
- Sympathetic transduction in humans: recent advances and methodological considerations.American journal of physiology. Heart and circulatory physiology · 2021Review
- Sex differences in cardiovascular autonomic control: introduction to the special issue.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSympathetic vasoconstriction plays a major role in the beat-to-beat control of blood pressure. To be effective and thus avoid dangerously high or low blood pressures, this mechanism relies upon transduction of sympathetic nerve activity at the level of the vasculature. However, recent evidence suggests that considerable variability exists in beat-to-beat vascular transduction, particularly between the sexes.
methodsWe reviewed the methods available for quantifying beat-to-beat transduction of muscle sympathetic nerve activity (MSNA) and explored the recent evidence for sex differences in vascular transduction. We paid specific attention to relationships between vascular transduction and factors such as resting levels of sympathetic nerve activity and baroreflex sensitivity.
resultsThere are two dominant methods now available for the quantification of beat-to-beat transduction of muscle sympathetic nerve activity at rest. Whilst there is some evidence to suggest that young females exhibit lower levels of vascular transduction, results vary depending on the method used and the direction of change in MSNA. Evidence suggests that compensatory relationships may exist between key components of neurovascular control, such as vascular transduction and resting levels of MSNA. Also consistent is the presence of such relationships in young males but not young females.
conclusionThe lack of significant relationships in young females may reflect the influence of vasodilator mechanisms that counteract sympathetic vasoconstriction. The assessment of vascular transduction following MSNA bursts and non-bursts in males and females, both young and older, may help to gain a mechanistic understanding of the prevalence of hypotensive and hypertensive disorders across the lifespan.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.