SynthesisEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2020
Osteolysis after cervical disc arthroplasty.
Synthesis in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- The lexicon for periprosthetic bone loss versus osteolysis after cervical disc arthroplasty: a systematic review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022Pooled it
- Explant analysis of two rhine cervical discs.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Coexistence of heterotopic ossification and anterior bone loss after multilevel cervical disc arthroplasty: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Complication Profiles Leading to Revision Surgery After Cervical Disc Arthroplasty.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2026Article
- Posterior migration of the mobile core in an unconstrained cervical disc replacement: a case report.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- The Total Disc Replacement Osteolysis Grading Scale - a simple, reliable and quantifiable tool for assessing, managing and reporting osteolysis after cervical total disc replacement.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Rates of Osteolysis for Commercially Available Cervical Disc Arthroplasty Devices in the United States: A Manufacturer and User Facility Device Experience Database Analysis.International journal of spine surgery · 2025Article
- Historical trends and future projections of cervical disc arthroplasty and removal cervical disc arthroplasty in the United States Medicare population.North American Spine Society journal · 2025Article
- The Future of Arthroplasty in the Spine.International journal of spine surgery · 2025Article
- Reoperation Strategy for Failure of Cervical Disc Arthroplasty at Index and Adjacent Levels.Journal of clinical medicine · 2025Review
- More anterior bone loss in middle vertebra after contiguous two-segment cervical disc arthroplasty.Journal of orthopaedic surgery and research · 2024Article
- Proposal for a classification system of radiographic bone changes after cervical disc replacement.Journal of orthopaedic surgery and research · 2024Article
- Heterotopic ossification, osteolysis and implant failure following cervical total disc replacement with the M6-C™ artificial disc.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Article
- Development and validation of a risk prediction model for osteoporosis in elderly patients with type 2 diabetes mellitus: a retrospective and multicenter study.BMC geriatrics · 2023Article
- Cervical Myelopathy Induced by Posterior Vertebral Body Osteolysis after Cervical Disc Arthroplasty.Journal of Korean Neurosurgical Society · 2023Article
- Anterior Bone Loss after Cervical Baguera C Disc versus Bryan Disc Arthroplasty.BioMed research international · 2023Article
- Antibiotic-impregnated calcium sulfate for the treatment of pediatric hematogenous osteomyelitis.BMC pediatrics · 2022Article
- Cervical and Lumbar Disc Arthroplasty: A Review of Current Implant Design and Outcomes.Bioengineering (Basel, Switzerland) · 2022Review
- A Bibliometric Analysis of the Top 100 Cited Articles in Anterior Cervical Discectomy and Fusion.Journal of pain research · 2022Article
- Letter to the Editor concerning "Osteolysis after cervical disc arthroplasty" by Joaquim AF, et al. (Eur Spine J; [2020]: doi: 10.1007/s00586-020-06,578-2).European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2020Article
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCervical disc arthroplasty (CDA) has become an increasingly popular treatment for cervical degenerative disc disease. One potential complication is osteolysis. However, current literature on this topic appears limited. The purpose of this study is to elucidate the incidence, aetiology, consequence, and subsequent treatment of this complication.
methodsA systematic literature review was performed according to the PRISMA guidelines. Studies discussing the causes, incidence and management of osteolysis after a CA were included.
resultsA total of nine studies were included. We divided these studies into two groups: (1) large case series in which an active radiological evaluation for osteolysis was performed (total = six studies), (2) case report studies, which discussed symptomatic cases of osteolysis (total = three). The incidence of asymptomatic osteolysis ranged from 8 to 64%; however, only one study reported an incidence of < 10% and when this case was excluded the incidence ranged from 44 to 64%. Severe asymptomatic bone loss (exposure of the implant) was found in less than 4% of patients. Bone loss from osteolysis appeared to occur early (< 1 year) after surgery and late (> 1 year) as well. Symptomatic patients with osteolysis often required revision surgery. These patients required removal of implant and conversion to fusion in the majority of the cases.
conclusionsOsteolysis after CDA is common; however, the majority of cases have only mild or asymptomatic presentations that do not require revision surgery. The timing of osteolysis varies significantly. This may be due to differences in the aetiology of osteolysis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.