Evidence map›Paper›PMID 32865119›Full record

ArticleGut microbes2020

Gut commensal microbiota and decreased risk for

Matthew Magruder, Emmanuel Edusei, Lisa Zhang, Shady Albakry, Michael J Satlin, Lars F Westblade, Line Malha, Christina Sze, Michelle Lubetzky, Darshana M Dadhania and 1 more

Open access · goldAbstract read
In one paragraph

Article in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

  1. Pooled it
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  6. LateiScience · 2026
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  19. A Bird's-Eye View of the Pathophysiologic Role of the Human Urobiota in Health and Disease: Can We Modulate It?Pathophysiology : the official journal of the International Society for Pathophysiology · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Matthew MagruderDivision of Nephrology and Hypertension, Department of Medicine, Weill Cornell Medicine , New York, NY, USA.
Emmanuel EduseiDivision of Nephrology and Hypertension, Department of Medicine, Weill Cornell Medicine , New York, NY, USA.
Lisa ZhangDivision of Nephrology and Hypertension, Department of Medicine, Weill Cornell Medicine , New York, NY, USA.
Shady AlbakryDivision of Nephrology and Hypertension, Department of Medicine, Weill Cornell Medicine , New York, NY, USA.
Michael J SatlinDivision of Infectious Diseases, Department of Medicine, Weill Cornell Medicine , New York, NY, USA.
Lars F WestbladeDivision of Infectious Diseases, Department of Medicine, Weill Cornell Medicine , New York, NY, USA.
Line MalhaDivision of Nephrology and Hypertension, Department of Medicine, Weill Cornell Medicine , New York, NY, USA.
Christina SzeDepartment of Urology, NewYork Presbyterian Hospital - Weill Cornell Medical Center , New York, NY, USA.ORCID 0000-0002-9891-8906
Michelle LubetzkyDivision of Nephrology and Hypertension, Department of Medicine, Weill Cornell Medicine , New York, NY, USA.
Darshana M DadhaniaDivision of Nephrology and Hypertension, Department of Medicine, Weill Cornell Medicine , New York, NY, USA.ORCID 0000-0002-7973-1521
John R LeeDivision of Nephrology and Hypertension, Department of Medicine, Weill Cornell Medicine , New York, NY, USA.
Cornell University · USNewYork–Presbyterian Hospital · US

Funding

Gut Microbiome, Acute Rejection, and Tacrolimus Dosing in Kidney TransplantationK23AI124464 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI LEE, JOHN RICHARD · 2016 to 2020
$944k
NIAID NIH HHS K23 AI124464
6 · The paper itself

Abstract

Urinary tract infection (UTI) is a common complication in kidney transplant recipients and can lead to significant morbidity and mortality. Recent evidence supports a role for the gut as a source for UTIs but little is known about the relationship between gut commensal bacteria and UTI development. We hypothesized that the abundance of gut commensal bacteria is associated with a lower risk of developing bacteriuria and UTIs. We performed gut microbiome profiling using 16S rRNA gene sequencing of the V4-V5 hypervariable region on 510 fecal specimens in 168 kidney transplant recipients. Fifty-one kidney transplant recipients (30%) developed

Indexed as

Gastrointestinal MicrobiomeAdolescentAdultAgedAged, 80 and overBacteriaChildDNA, BacterialEnterobacteriaceaeEnterobacteriaceae InfectionsFecesFemaleHumansKidney TransplantationMaleMiddle AgedDNA, BacterialRNA, Ribosomal, 16SbacteriuriaEnterobacteriaceaeFaecalibacteriumLactobacillusMicrobiotaRomboutsiaurinary tract infection

Identifiers

PMID32865119
PMCPMC7524266
OpenAlexW3081544587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.