Evidence map›Paper›PMID 32864980›Full record

ReviewAmerican journal of Alzheimer's disease and other dementias

Unwinding Complexities of Diabetic Alzheimer by Potent Novel Molecules.

Sumeet Gupta, Anroop Nair, Vikas Jhawat, Nazia Mustaq, Abhishek Sharma, Meenakshi Dhanawat, Shah Alam Khan

Abstract readReview
In one paragraph

Review in American journal of Alzheimer's disease and other dementias. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Associations Between Diabetes Mellitus and Neurodegenerative Diseases.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Review
  6. Preventive nutrition and food science · 2022
    Article
  7. Insulin and Insulin Resistance in Alzheimer's Disease.International journal of molecular sciences · 2021
    Review
  8. Review
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sumeet GuptaDepartment of Pharmacology, MM College of Pharmacy, MM (Deemed to be University), Mullana (Ambala), Haryana, India.ORCID 0000-0003-2980-7791
Anroop NairDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Kingdom of Saudi Arabia.ORCID 0000-0003-2850-8669
Vikas JhawatDepartment of Pharmaceutical Sciences, G. D Goenka University, Gurugram, Haryana, India.
Nazia MustaqDepartment of Pharmacology, MM College of Pharmacy, MM (Deemed to be University), Mullana (Ambala), Haryana, India.
Abhishek SharmaDepartment of Pharmacology, MM College of Pharmacy, MM (Deemed to be University), Mullana (Ambala), Haryana, India.
Meenakshi DhanawatDepartment of Pharmaceutical Sciences, MM College of Pharmacy, MM (Deemed to be University), Mullana (Ambala), Haryana, India.
Shah Alam KhanDepartment of Pharmacy, Oman Medical College, Muscat, Oman.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus is one of the aggressive disorders in global society. No pharmacotherapy is available for permanent diabetes cure, although management is possible with drugs and physical activities. One of the recent complications noticed in type 2 diabetes mellitus includes diabetes-induced Alzheimer. It has been proposed that the possible diabetes-induced Alzheimer could be of type 3 diabetes. A variety of cross-sectional studies have proved that type 2 diabetes mellitus is one of the factors responsible for the pathophysiology of Alzheimer. New drug molecules developed by pharmaceutical companies with adequate neuroprotective effect have demonstrated their efficacy in treatment of Alzheimer in various preclinical diabetic studies. Patients of type 2 diabetes mellitus may show the benefit with existing drugs but may not cause complete cure. Extensive studies are being carried out to find new drug molecules that show their potential as antidiabetic drug and could treat type 2 diabetes-induced Alzheimer as well. This review provides an overview about the recent advancement in pharmacotherapy of diabetes-induced Alzheimer. The pathomechanistic links between diabetes and Alzheimer as well as neurochemical changes in diabetes-induced Alzheimer are also briefed.

Indexed as

Alzheimer DiseaseCross-Sectional StudiesDiabetes Mellitus, Type 2HumansHypoglycemic AgentsHypoglycemic AgentsAlzheimerdiabetes mellitusnew drug moleculespathophysiologypharmacotherapy

Identifiers

PMID32864980
PMCPMC10623924

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.