Evidence map›Paper›PMID 32864903›Full record

ArticleAdvanced healthcare materials2021

Different PEG-PLGA Matrices Influence In Vivo Optical/Photoacoustic Imaging Performance and Biodistribution of NIR-Emitting π-Conjugated Polymer Contrast Agents.

Paul Robert Neumann, Frank Erdmann, Joost Holthof, Gabriela Hädrich, Mark Green, Jianghong Rao, Lea Ann Dailey

Abstract read
In one paragraph

Article in Advanced healthcare materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Paul Robert NeumannDepartment of Pharmaceutical Technology and Biopharmaceutics, Martin-Luther-University Halle-Wittenberg, 06120, Halle (Saale), Germany.ORCID 0000-0002-0003-6332
Frank ErdmannInstitute of Pharmacy, Department of Pharmacology, Martin-Luther-University Halle-Wittenberg, 06120, Halle (Saale), Germany.ORCID 0000-0001-5261-0984
Joost HolthofFUJIFILM Visualsonics, Joop Geesinkweg 140, Amsterdam, 1114 AB, The Netherlands.
Gabriela HädrichDepartment of Pharmaceutical Technology and Biopharmaceutics, Martin-Luther-University Halle-Wittenberg, 06120, Halle (Saale), Germany.ORCID 0000-0002-2360-8882
Mark GreenDepartment of Physics, King's College London, London, WC2R 2LS, UK.
Jianghong RaoDepartment of Radiology and Chemistry, Stanford University, Stanford, CA, 94305-5484, USA.ORCID 0000-0002-5143-9529
Lea Ann DaileyDepartment of Pharmaceutical Technology and Biopharmacy, University of Vienna, Vienna, 1090, Austria.ORCID 0000-0002-4908-7122

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The π-conjugated polymer poly[2,6-(4,4-bis-(2-ethylhexyl)-4H-cyclopenta[2,1-b;3,4-b0]-dithiophene)-alt-4,7-(2,1,3-benzothiadiazole)] (PCPDTBT) with deep-red/near-infrared (NIR) absorption and emission has been investigated as a contrast agent for in vivo optical and photoacoustic imaging. PCPDTBT is encapsulated within poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide) (PEG

Indexed as

NanoparticlesPhotoacoustic TechniquesAnimalsContrast MediaMicePolyestersPolyethylene GlycolsPolymersTissue DistributionContrast MediaPolyesterspolyethylene glycol-poly(lactide-co-glycolide)Polyethylene GlycolsPolymersconjugated polymer nanoparticlesPCPDTBTPEG-PLGAphotoacoustic imaging

Identifiers

PMID32864903
PMCPMC11469236

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.