Evidence map›Paper›PMID 32864830›Full record

ArticleJournal of clinical laboratory analysis2020

Analysis of serum gastrin-17 and Helicobacter pylori antibody in healthy Chinese population.

Wenjun Liu, Youxiang Sun, Yulin Yuan

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Observational
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  7. Detection ofThe Journal of international medical research · 2024
    Article
  8. Review
  9. Effects of Infection with Different Types ofInternational journal of general medicine · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Evaluation of Anti-Diagnostics (Basel, Switzerland) · 2022
    Article
  15. Article
  16. Screening for gastric cancer in China: Advances, challenges and visions.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2021
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Wenjun LiuDepartment of Laboratory Medicine, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.ORCID https://orcid.org/0000-0003-3964-1422
Youxiang SunDepartment of Laboratory Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China.
Yulin YuanDepartment of Laboratory Medicine, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
The People's Hospital of Guangxi Zhuang Autonomous Region · CNQingdao University · CN

Funding

self-funded research project of The Health Committee of Guangxi Zhuang Autonomous Regions Z2016629
6 · The paper itself

Abstract

backgroundGastrin-17 (G-17) and Helicobacter pylori (H pylori) antibody are widely used in the screening of gastric diseases, especially in gastric cancer. In this study, we aimed to evaluate the value of G-17 and H pylori antibody in gastric disease screening.

methodsHealthy males and females (1368 and 1212, respectively) aged between 21-80 years were recruited for the study. Serum G-17 value was measured using ELISA, and H pylori antibodies were measured using Western blotting. Statistical analyses were performed using the chi-square, Mann-Whitney U, and Kruskal-Wallis H tests.

resultsSerum G-17 level was higher in the H pylori-positive group than in the negative group. Serum G-17 level was higher in the type 1 H pylori-positive group than in the type 2 H pylori-positive group. Further, serum G-17 level was higher in females than in males and showed significant differences among different age-groups, with changes in trend proportional to the age. The positive rate of H pylori infection in all the subjects was 58.29% and did not show a significant difference between males and females. However, it showed significant differences among different age-groups, with the changing trend proportional to the age.

conclusionAnalysis of serum G-17 level and H pylori antibody typing is valuable in gastric disease screening. Every laboratory should establish its own reference interval for G-17 level.

Indexed as

AdultAgedAged, 80 and overAntibodies, BacterialChinaFemaleGastrinsHelicobacter InfectionsHelicobacter pyloriHumansMaleMiddle AgedRetrospective StudiesStomach DiseasesYoung AdultAntibodies, Bacterialgastrin 17Gastrinsagegastric diseasegastringenderHelicobacter pylori antibody

Identifiers

PMID32864830
PMCPMC7755801
OpenAlexW3081703251

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.