Evidence map›Paper›PMID 32864708›Full record

ArticleCurrent microbiology2020

Enzymatic Modulators from Induratia spp.

Andréa Patrícia da Silva Pomposo Bastos, Patrícia Gomes Cardoso, Ítalo Augusto Férrer Melo Santos, Marcus Vinicius Cardoso Trento, Laura Cristina Jardim Porto, Silvana Marcussi

Abstract read
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In one paragraph

Article in Current microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Andréa Patrícia da Silva Pomposo BastosNutrition Department (Departamento de Nutrição), Universidade Federal de Lavras (UFLA), Lavras, MG, 37200-900, Brazil.
Patrícia Gomes CardosoBiology Department (Departamento de Biologia), BIOGEN Laboratory (Laboratório BIOGEN), Universidade Federal de Lavras (UFLA), Lavras, MG, 37200-900, Brazil. patricia@ufla.br.
Ítalo Augusto Férrer Melo SantosBiology Department (Departamento de Biologia), BIOGEN Laboratory (Laboratório BIOGEN), Universidade Federal de Lavras (UFLA), Lavras, MG, 37200-900, Brazil.
Marcus Vinicius Cardoso TrentoChemistry Department (Departamento de Química), Biochemistry Laboratory (Laboratório de Bioquímica), Universidade Federal de Lavras (UFLA), Lavras, MG, 37200-900, Brazil.
Laura Cristina Jardim PortoNutrition Department (Departamento de Nutrição), Universidade Federal de Lavras (UFLA), Lavras, MG, 37200-900, Brazil.
Silvana MarcussiChemistry Department (Departamento de Química), Biochemistry Laboratory (Laboratório de Bioquímica), Universidade Federal de Lavras (UFLA), Lavras, MG, 37200-900, Brazil.
Universidade Federal de Lavras · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present work, ethyl acetate extracts, consisting of non-volatile compounds, from the culture of endophytic fungi isolated from coffee plants, Induratia coffeana and Induratia yucatanensis, were prospected in enzyme modulation tests that act in human hemostasis. Dry extracts of the fungi were diluted in dimethyl sulfoxide p.a. 99.9% (DMSO), and then tested. Bothrops atrox venom was used as an enzyme source and tool to induce the activities. Prior to the evaluation of the activities, incubations of the extracts with the venom were performed in the proportions 1: 0.01, 1: 0.25, 1: 0.5, and 1: 1 (venom: extract; mass: mass). The extracts of all fungi promoted a significant increase in the clotting time induced by the venom, which was even longer when the extracts were previously incubated with the citrated plasma. The activity of phospholipases A

Indexed as

Plant ExtractsXylarialesHumansPhospholipases A2Phospholipases A2Plant Extracts

Identifiers

PMID32864708
OpenAlexW3082660660

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.