ArticleCerebral cortex communications2020
Neural Responses to Reward in a Gambling Task: Sex Differences and Individual Variation in Reward-Driven Impulsivity.
Article in Cerebral cortex communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 32 citations in OpenAlex.
- Sex and pubertal stage as moderators of the association between resting-state connectivity of striatal circuitry and reward sensitivity in the Adolescent Brain Cognitive Development study.Developmental cognitive neuroscience · 2026Article
- Gambling Disorder as a Behaviorally Driven Systemic Medical Condition: From Reward Circuitry to Multi-System Morbidity.Clinics and practice · 2026Review
- Phenotypes associated with problematic online gaming and gambling: A clustering approach among young adults.Addictive behaviors reports · 2026Article
- Sex differences in resting-state hypothalamic connectivity and its relationship with negative emotion and behavior measures in young adults.Brain structure & function · 2026Article
- Robust but independent sex differences in human brain function, structure, and behavior.Nature communications · 2026Article
- Sex-specific neural responses to smartphone cues in young adults.Biology of sex differences · 2026Article
- Article
- Mechanisms and interventions promoting healthy frontostriatal dynamics in obsessive-compulsive disorder.Nature communications · 2025Article
- How individual BMI affected general cognitive ability in young adults: a moderated chain mediation model.Frontiers in public health · 2025Article
- Functional Networks of Reward and Punishment Processing and Their Molecular Profiles Predicting the Severity of Young Adult Drinking.Brain sciences · 2024Article
- Sex differences in externalizing and internalizing traits and ventral striatal responses to monetary loss.Journal of psychiatric research · 2023Article
- Mapping frontoinsular cortex from diffusion microstructure.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Loss and Frontal Striatal Reactivities Characterize Alcohol Use Severity and Rule-Breaking Behavior in Young Adult Drinkers.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2022Article
- A Model Guided Approach to Evoke Homogeneous Behavior During Temporal Reward and Loss Discounting.Frontiers in psychiatry · 2022Article
- Alcohol use severity and the neural correlates of the effects of sleep disturbance on sustained visual attention.Journal of psychiatric research · 2021Article
- Perceived friendship and binge drinking in young adults: A study of the Human Connectome Project data.Drug and alcohol dependence · 2021Article
- Neural correlates of individual variation in two-back working memory and the relationship with fluid intelligence.Scientific reports · 2021Article
- Sex differences in neural responses to reward and the influences of individual reward and punishment sensitivity.BMC neuroscience · 2021Article
- Sex Differences in Neural Responses to the Perception of Social Interactions.Frontiers in human neuroscience · 2020Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Previous work suggests sex differences in reward sensitivity. However, it remains unclear how men and women differ in the neural processes of reward-driven impulsivity. With a data set of 968 subjects (502 women) curated from the Human Connectome Project, we investigated sex differences in regional activations to reward and to punishment in a gambling task. Individual variations in reward-driven impulsivity were quantified by the difference in reaction time between reward and punishment blocks in the gambling task, as well as by a behavioral measure of delay discounting. At a corrected threshold, men and women exhibited significant differences in regional activations to reward and to punishment. Longer reaction times during reward versus punishment blocks, indicative of more cautious responding, were associated with left-hemispheric lateral prefrontal cortical activation to reward in men but not women. Steeper discounting was associated with higher activation to reward in the right-hemispheric dorsal anterior cingulate cortex and angular gyrus in women but not men. These sex differences were confirmed in slope tests. Together, the results highlight the sex-specific neural processes of reward-driven impulsivity with left-hemispheric prefrontal cortex supporting impulse control in men and right-hemispheric saliency circuit playing a more important role in diminished impulse control in women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.