ArticleCurrent opinion in toxicology2020
Intestinal Microbiome and Metal Toxicity.
Article in Current opinion in toxicology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Major heavy metals and human gut microbiota composition: a systematic review with nutritional approach.Journal of health, population, and nutrition · 2025Pooled it
- Amelioration of intestinal barrier function and reduction of blood lead level in adult women with recurrent spontaneous abortion by a novel product of dietary fiber mixture, Holofood.Journal of health, population, and nutrition · 2023Trial
- Microbial metabolite Urolithin A protects against inorganic arsenic-induced gut barrier dysfunction in humanizedGut microbes · 2026Article
- Bioaccessibility and Risk Assessment of Trace Elements in Mealworms Using Continuous On-Line Leaching Coupled with Inductively Coupled Plasma Mass Spectrometry.Foods (Basel, Switzerland) · 2026Article
- Gut microbiota-metabolism axis in digestive tumors: Emerging targets for novel therapies (Review).Experimental and therapeutic medicine · 2026Review
- Effects of heavy metal exposure on oral microbial communities in women with different menopausal status.Microbiology spectrum · 2026Article
- Gut as a Target of Ochratoxin A: Toxicological Insights and the Role of Microbiota.International journal of molecular sciences · 2025Review
- Trace Element Exposure during Pregnancy Has a Persistent Influence on Perinatal Gut Microbiota in Mother-Infant Dyads.Environmental science & technology · 2025Article
- Heavy Metal-Gut Microbiota Interactions: Probiotics Modulation and Biosensors Detection.Biosensors · 2025Review
- Toxic metals impact gut microbiota and metabolic risk in five African-origin populations.Gut microbes reports · 2025Article
- Association between heavy metal exposure and bacterial vaginosis: A cross-sectional study.PloS one · 2025Article
- Guardians of the Gut: Harnessing the Power of Probiotic Microbiota and Their Exopolysaccharides to Mitigate Heavy Metal Toxicity in Human for Better Health.Probiotics and antimicrobial proteins · 2024Review
- Mechanisms of Metal-Induced Hepatic Inflammation.Current environmental health reports · 2024Review
- Mercury and Arctic Char Gill Microbiota Correlation in Canadian Arctic Communities.Microorganisms · 2024Article
- Diverse mechanisms by which chemical pollutant exposure alters gut microbiota metabolism and inflammation.Environment international · 2024Review
- Metagenomics analysis of mice gut microbiome to unravel the role of metal exposure and piperine.Access microbiology · 2024Article
- Addressing the Missing Links in Cardiovascular Aging.Clinical interventions in aging · 2024Review
- Cobalt-induced neuro-behavioural alterations are accompanied by profound Purkinje cell and gut-associated responses in rats.Environmental analysis, health and toxicology · 2023Article
- Assessing the role of the gut microbiome at the interface between environmental chemical exposures and human health: Current knowledge and challenges.Environmental pollution (Barking, Essex : 1987) · 2022Review
- Effects of a novel probiotic mixture on the modulation of brain and intestine Aquaporin-4 gene expression in rats exposed to Cadmium.Metabolic brain disease · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The human gut microbiome is considered critical for establishing and maintaining intestinal function and homeostasis throughout life. Evidence for bidirectional communication with the immune and nervous systems has spawned interest in the microbiome as a key factor for human and animal health. Consequently, appreciation of the microbiome as a target of xenobiotics, including environmental pollutants such as heavy metals, has risen steadily because disruption of a healthy microbiome (dysbiosis) has been linked to unfavorable health outcomes. Thus, toxicology must consider toxicant effects on the host's microbiome as an integral part of the holobiont. We discuss current findings on the impact of toxic metals on the composition, diversity, and function of the gut microbiome as well as the modulation of metal toxicity by the microbiome. Present limitations and future needs in elucidating microbiome-metal interactions and the potential of harnessing beneficial traits of the microbiota to counteract metal toxicity are also considered.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.