ArticleLaryngoscope investigative otolaryngology2020
Pressure abnormalities in patients with Zenker's diverticulum using pharyngeal high-resolution manometry.
Article in Laryngoscope investigative otolaryngology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Esophageal and Oropharyngeal Dysphagia: Clinical Recommendations From the United European Gastroenterology and European Society for Neurogastroenterology and Motility.United European gastroenterology journal · 2025Guideline
- Normative High-Resolution Pharyngeal Manometry: Impact of Age, Size of System, and Sex on Primary Metrics and Pressure Stability.Dysphagia · 2024Article
- MSCT study for adult esophageal diverticulum with secondary broncho-esophageal fistula.Journal of cardiothoracic surgery · 2024Article
- Association of the "Jet Phenomenon" with Positive Symptom Outcome Following Surgical Treatment of Cricopharyngeus Muscle Dysfunction.Dysphagia · 2023Article
- Esophageal diverticula: from diagnosis to therapeutic management-narrative review.Journal of thoracic disease · 2023Review
- Botulinum toxin injection combined with traditional swallowing rehabilitation improved cricopharyngeal dysfunction in neuromyelitis optica spectrum disorder: A case report.Frontiers in neurology · 2022Article
- Correlating Dysphagia Severity with Fluoroscopic Parameters in Patients with Zenker's Diverticulum.Dysphagia · 2021Article
- The upper esophageal sphincter in the high-resolution manometry era.Langenbeck's archives of surgery · 2021Review
- Bronchoesophageal fistula secondary to esophageal diverticulum in an adult: a case report and literature review.The Journal of international medical research · 2021Review
- Pressure abnormalities in patients with Zenker's diverticulum using pharyngeal high-resolution manometry.Laryngoscope investigative otolaryngology · 2020Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectivesZenker's diverticulum is associated with reduced cricopharyngeal compliance and abnormal intrabolus pressure. However, it is unclear how the pharynx compensates for these deficits. Developments in manometric technology have improved our ability to capture pharyngeal pressure events. This study aims to describe the pharyngeal-upper esophageal sphincter (UES) pressure profile during swallowing in patients with Zenker's diverticulum.
methodsHigh-resolution manometry was performed on 11 patients with symptomatic Zenker's diverticulum and 11 age- and sex-matched healthy controls during 10 mL liquid swallowing tasks. Pharyngeal and UES pressure magnitudes, durations, and integrals were compared between patients and controls using independent
resultsCompared with healthy controls, patients with Zenker's diverticulum exhibited pressure abnormalities in the UES region. While baseline and pre-opening maximum pressures were not different, residual pressures were elevated (
conclusionThis study used high-resolution manometry to characterize pharyngeal pressure dynamics in patients with Zenker's diverticulum. The changes occurring at the cricopharyngeus appear to result in persistent UES pressurization during UES opening, rather than high tonic resting pressure. Pharyngeal-UES pressure gradients, critical to bolus passage, were also preserved in this patient population. LEVEL OF EVIDENCE: 3b.
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