ArticleLaryngoscope investigative otolaryngology2020
The value of narrowband imaging using the Ni classification in the diagnosis of laryngeal cancer.
Article in Laryngoscope investigative otolaryngology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Optical Imaging Technologies and Clinical Applications in Gastrointestinal Endoscopy.Diagnostics (Basel, Switzerland) · 2025Review
- Binary Classification of Laryngeal Images Utilising ResNet-50 CNN Architecture.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- Laryngeal Carcinoma Characteristics Associated with Positive Margins and Endoscopic Understaging.Diagnostics (Basel, Switzerland) · 2025Article
- Observational
- Correlation of Narrow Band Imaging Patterns with Histopathology Reports in Head and Neck Lesions.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Clinical significance of type IV vascularization of laryngeal lesions according to the Ni classification.Frontiers in oncology · 2024Article
- Treatment of Early Glottic cancer with Transoral Laser Microsurgery: An Australian Experience.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- A Case Report of Rare Vocal Cord Hemangioendothelioma in a Paediatric Larynx.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- Narrative Review of Classification Systems Describing Laryngeal Vascularity Using Advanced Endoscopic Imaging.Journal of clinical medicine · 2022Review
- The value of narrowband imaging using the Ni classification in the diagnosis of laryngeal cancer.Laryngoscope investigative otolaryngology · 2020Article
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7 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
introductionNarrowband imaging (NBI) is a special endoscopic optical enhancement setting allowing better visualization of mucosal microvasculature compared to white light endoscopy. This study evaluates the validity of NBI using the Ni classification in the detection and differentiation of severe dysplasia (SD) and glottic squamous cell carcinoma (SCC).
methodsPatients with suspicious vocal cord lesions underwent conventional white light endoscopy followed by clinically indicated biopsy. At the same time, NBI images were obtained and graded independently. Lesions were graded from I to V according to the Ni classification and compared to histopathological findings.
resultsFifty-two patients were included in this study (40 SCC and 12 SD). The sensitivity and specificity of NBI in diagnosing laryngeal cancer was 95.0% (CI, 83.9%-99.4%) and 83.3% (CI, 51.6%-97.9%), respectively. The negative likelihood ratio was 0.06. Higher Ni grades correlated very strongly with more advanced disease.
conclusionsNBI using the Ni classification is a sensitive diagnostic tool for the detection and differentiation of early neoplastic and preneoplastic glottic lesions. As higher Ni classification correlates strongly with advanced disease, it serves as a useful adjunct to white light endoscopy in the diagnosis of laryngeal cancer.Level of Evidence: Level IV.
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