ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2020
cCOG: A web-based cognitive test tool for detecting neurodegenerative disorders.
Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Primary care detection of Alzheimer's disease using a self-administered digital cognitive test and blood biomarkers.Nature medicine · 2025Article
- Towards a national registry for Alzheimer's disease and related dementias: rationale, design, and initial observations of the ABOARD cohort.Alzheimer's research & therapy · 2025Article
- Smartphone- and Tablet-Based Tools to Assess Cognition in Individuals With Preclinical Alzheimer Disease and Mild Cognitive Impairment: Scoping Review.Journal of medical Internet research · 2025Article
- Feasibility of computerized motor, cognitive and speech tests in the home: Analysis of TAS Test in 2,300 older adults.The journal of prevention of Alzheimer's disease · 2025Article
- Alzheimer's Disease and Vascular Dementia, Connecting and Differentiating Features.Current Alzheimer research · 2025Review
- Computerized decision support to optimally funnel patients through the diagnostic pathway for dementia.Alzheimer's research & therapy · 2024Article
- Rationale and design of the BeyeOMARKER study: prospective evaluation of blood- and eye-based biomarkers for early detection of Alzheimer's disease pathology in the eye clinic.Alzheimer's research & therapy · 2024Observational
- Observational
- Use of a digital tool to support the diagnostic process in memory clinics-a usability study.Alzheimer's research & therapy · 2024Article
- Machine Learning and Digital Biomarkers Can Detect Early Stages of Neurodegenerative Diseases.Sensors (Basel, Switzerland) · 2024Review
- cCOG Web-Based Cognitive Assessment Tool.Methods in molecular biology (Clifton, N.J.) · 2024Article
- TWINGEN - protocol for an observational clinical biobank recall and biomarker study to identify individuals with high risk of Alzheimer's disease.medRxiv : the preprint server for health sciences · 2023Article
- Optimizing cCOG, a Web-based tool, to detect dementia with Lewy Bodies.Alzheimer's & dementia (Amsterdam, Netherlands) · 2022Article
- Assessing the Views of Professionals, Patients, and Care Partners Concerning the Use of Computer Tools in Memory Clinics: International Survey Study.JMIR formative research · 2021Article
- Web-Based Assessment of the Phenomenology of Autobiographical Memories in Young and Older Adults.Brain sciences · 2021Article
- cCOG: A web-based cognitive test tool for detecting neurodegenerative disorders.Alzheimer's & dementia (Amsterdam, Netherlands) · 2020Article
- Article
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21 authors.
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Abstract
introductionWeb-based cognitive tests have potential for standardized screening in neurodegenerative disorders. We examined accuracy and consistency of cCOG, a computerized cognitive tool, in detecting mild cognitive impairment (MCI) and dementia.
methodsClinical data of 306 cognitively normal, 120 mild cognitive impairment (MCI), and 69 dementia subjects from three European cohorts were analyzed. Global cognitive score was defined from standard neuropsychological tests and compared to the corresponding estimated score from the cCOG tool containing seven subtasks. The consistency of cCOG was assessed comparing measurements administered in clinical settings and in the home environment.
resultscCOG produced accuracies (receiver operating characteristic-area under the curve [ROC-AUC]) between 0.71 and 0.84 in detecting MCI and 0.86 and 0.94 in detecting dementia when administered at the clinic and at home. The accuracy was comparable to the results of standard neuropsychological tests (AUC 0.69-0.77 MCI/0.91-0.92 dementia). DISCUSSION: cCOG provides a promising tool for detecting MCI and dementia with potential for a cost-effective approach including home-based cognitive assessments.
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