Evidence map›Paper›PMID 32864392›Full record

ArticleBioelectronic medicine2020

Determining grasp selection from arm trajectories via deep learning to enable functional hand movement in tetraplegia.

Nikunj Bhagat, Kevin King, Richard Ramdeo, Adam Stein, Chad Bouton

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Bioelectronic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03385005 early_phase1completednot on this map

Evaluating Neuromuscular Stimulation for Restoring Hand Movements

TypeinterventionalSponsorNorthwell HealthRan2017 to 2023Enrolled9ConditionsHealthy Volunteers, Spinal Cord Injury Cervical, Physical and Rehabilitation MedicineArmsParticipants will receive neuromuscular electrical stimulation via an investigational (not FDA approved) neuromuscular stimulator.
NCT04755699 early_phase1recruitingnot on this map

Chronic Transcutaneous Stimulation to Promote Motor Function and Recovery in Individuals With Paralysis or Paresis

TypeinterventionalSponsorNorthwell HealthRan2020 to 2028Enrolled64ConditionsHealthy Volunteers, Spinal Cord Injury, Stroke, ParalysisArmsTranscutaneous Electrical Stimulation
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Nikunj BhagatFeinstein Institutes for Medical Research at Northwell Health, Manhasset, NY USA.ORCID 0000-0002-0158-2861
Kevin KingFeinstein Institutes for Medical Research at Northwell Health, Manhasset, NY USA.
Richard RamdeoFeinstein Institutes for Medical Research at Northwell Health, Manhasset, NY USA.
Adam SteinZucker School of Medicine at Hofstra/Northwell, Hempstead, NY USA.
Chad BoutonFeinstein Institutes for Medical Research at Northwell Health, Manhasset, NY USA.
Northwell Health · USFeinstein Institute for Medical Research · USHofstra University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCervical spinal cord injury severely affects grasping ability of its survivors. Fortunately, many individuals with tetraplegia retain residual arm movements that allow them to reach for objects. We propose a wearable technology that utilizes arm movement trajectory information and deep learning methods to determine grasp selection. Furthermore, we combined this approach with neuromuscular stimulation to determine if self-driven functional hand movement could be enabled in spinal cord injury participants.

methodsTwo cervical SCI participants performed arbitrary and natural reaching movements toward target objects in three-dimensional space, which were recorded using an inertial sensor worn on their wrist. Time series classifiers were trained to recognize the trajectories using either a Dynamic Time Warping (DTW) algorithm or a Long Short-Term Memory (LSTM) recurrent neural network

resultsParticipants were able to consistently perform arbitrary two-dimensional and three-dimensional arm movements which could be classified with high accuracy. Furthermore, it was found that natural reaching trajectories for two different target objects (requiring two different grasp types) were distinct and also discriminable with high accuracy. In offline comparisons, LSTM (mean accuracies 99%) performed significantly better than DTW (mean accuracies 86 and 83%) for both arbitrary and natural reaching movements, respectively. Type I and II errors occurred more frequently for DTW (up to 60 and 15%, respectively), whereas it stayed under 5% for LSTM. Also, DTW achieved online accuracy of 79%.

conclusionsWe demonstrate the feasibility of utilizing arm trajectory information to determine grasp selection using a wearable inertial sensor along with DTW and deep learning methods. Importantly, this technology can be successfully used to control neuromuscular stimulation and restore functional independence to individuals living with paralysis.

trial registrationNCT, NCT03385005. Registered September 26, 2017.

Indexed as

IMUInertial measurement unitMachine learningNeural networksNeuromuscular stimulationSpinal cord injuryWearable

Identifiers

PMID32864392
PMCPMC7449026
OpenAlexW3080548518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.