Evidence map›Paper›PMID 32864297›Full record

ArticleCurrent treatment options in pediatrics2019

Congenital Anomalies of the Kidney and Urinary Tract: A Clinical Review.

Emily Stonebrook, Monica Hoff, John David Spencer

Open access · greenAbstract read
In one paragraph

Article in Current treatment options in pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
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  19. Bilateral Renal Ectopia-Prenatal Diagnosis.Diagnostics (Basel, Switzerland) · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Emily StonebrookPediatric Nephrology Fellowship Program, Division of Pediatric Nephrology, Nationwide Children's Hospital, Columbus, OH USA.
Monica HoffPediatrics Residency Program, Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH, USA.
John David SpencerDivision of Pediatric Nephrology, Nationwide Children's Hospital, Columbus, OH USA.
Nationwide Children's Hospital · US

Funding

Linking Insulin Signaling to Antimicrobial Peptide Production and the Kidney's Antibacterial DefensesR01DK114035 · NIDDK · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI SPENCER, JOHN DAVID · 2018 to 2021
$1.4M
Ribonuclease 7: Antimicrobial Activity in the Human Kidney and Urinary TractK08DK094970 · NIDDK · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI SPENCER, JOHN DAVID · 2012 to 2016
$645k
NIDDK NIH HHS K08 DK094970NIDDK NIH HHS L40 DK099837NIDDK NIH HHS R01 DK114035
6 · The paper itself

Abstract

purpose of reviewThis review highlights the most common congenital anomalies of the kidney and urinary tract (CAKUT) that are encountered in pediatric practices. CAKUT are the most common cause of prenatally diagnosed developmental malformations and encompass a spectrum of disorders impacting lower urinary tract development as well as kidney development and function. In pediatric and adolescent populations, developmental abnormalities are the leading cause of end-stage kidney disease. The goal of this review is to provide pediatric providers a framework for appropriate clinical management as well as highlight when referral to subspecialty care is needed. RECENT

findingsWhile the exact etiologies of CAKUT are not completely defined, new evidence demonstrates that genetic and molecular changes impact embryonic kidney and urinary tract development. As a result, phenotypes and clinical outcomes may be affected. SUMMARY: Because pediatric providers provide front-line care to children and adolescents with developmental kidney and urinary tract anomalies, updated knowledge of CAKUT pathogenesis, embryology, clinical management, and patient outcomes is needed. This manuscript reviews CAKUT etiologies and essential diagnostic, prognostic, and management strategies.

Indexed as

Congenital Kidney AnomaliesEmbryologyGeneticsNephrologyPediatricsUrology

Identifiers

PMID32864297
PMCPMC7451090
OpenAlexW2950171207

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.