ArticleJRSM cardiovascular disease
A brief report on the effects of vasoactive agents on peripheral venous waveforms in a porcine model.
Article in JRSM cardiovascular disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 6 citations in OpenAlex.
- A prospective, observational study of non-invasive venous waveform analysis (NIVA) for the detection of acute low volume blood loss in humans.Journal of clinical anesthesia · 2025Observational
- Hemodynamic Parameters in the Assessment of Fluid Status in a Porcine Hemorrhage and Resuscitation Model.Anesthesiology · 2021Article
- Physiology and clinical utility of the peripheral venous waveform.JRSM cardiovascular diseaseReview
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesNon-invasive venous waveform analysis (NIVA) is a recently described, novel technique to assess intravascular volume status. Waveforms are captured with a piezoelectric sensor; analysis in the frequency domain allows for calculation of a "NIVA value" that represents volume status. The aim of this report was to determine the effects of vasoactive agents on the venous waveform and calculated NIVA values.
designPorcine experimental model.
settingOperating theatre.
participantsA piezoelectric sensor was secured over the surgically exposed saphenous vein in eight anesthetized pigs.
main outcome measuresNIVA value, pulmonary capillary wedge pressure (PCWP), and mean arterial pressure prior to and post intravenous administration of 150-180 µg of phenylephrine or 100 µg of sodium nitroprusside.
resultsPhenylephrine led to a decrease in NIVA value (mean 9.2 vs. 4.6,
conclusionsVasoactive agents lead to changes in non-invasively obtained venous waveforms in euvolemic pigs, highlighting a potential limitation in the ability to NIVA to estimate static volume in this setting. Further studies are indicated to understand the effects of vasoactive agents in the setting of hypovolemia and hypervolemia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.